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Frequency and Clinical Implications of Discordant Creatine Kinase-MB and Troponin Measurements in Acute Coronary Syndromes

L. Kristin Newby, MD, MHS, FACC^_*,_*, Matthew T. Roe, MD, MHS, FACC^_*, Anita Y. Chen, MS^_*, E. Magnus Ohman, MD, FACC, Robert H. Christenson, PhD, Charles V. Pollack, Jr, MD, MA, James W. Hoekstra, MD^||, W. Frank Peacock, MD^¶, Robert A. Harrington, MD, FACC^_*, Robert L. Jesse, MD, PhD, FACC^_**, W. Brian Gibler, MD, Eric D. Peterson, MD, MPH, FACC^_* the CRUSADE Investigators

^_*Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina
Division of Cardiology, University of North Carolina-Chapel Hill, Chapel Hill, North Carolina
Department of Pathology, University of Maryland, Baltimore, Maryland
Department of Emergency Medicine, Pennsylvania Hospital, Philadelphia, Pennsylvania
^|| Department of Emergency Medicine, Wake Forest University Health Sciences, Winston-Salem, North Carolina
^¶ Department of Emergency Medicine, Cleveland Clinic Foundation, Cleveland, Ohio
^_** Division of Cardiology, Medical College of Virginia and Veterans Administration Medical Center, Richmond, Virginia
Department of Emergency Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio

View larger version (10K): [in a new window]   Figure 1 Odds ratios with 95% confidence intervals for acute use of glycoprotein (GP) IIb/IIIa inhibitors, clopidogrel, and an early invasive management strategy. CK-MB = creatine kinase-MB; cTn = cardiac troponin.