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J Am Coll Cardiol, 2010; 55:342-349, doi:10.1016/j.jacc.2009.11.010
© 2010 by the American College of Cardiology Foundation
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A High Ankle Brachial Index Is Associated With Greater Left Ventricular Mass

MESA (Multi-Ethnic Study of Atherosclerosis)

Joachim H. Ix, MD, MAS*,{dagger},{ddagger},*, Ronit Katz, DPhil§, Carmen A. Peralta, MD, MAS#,**, Ian H. de Boer, MD, MS||, Matthew A. Allison, MD, MPH{dagger}, David A. Bluemke, MD, PhD{dagger}{dagger}, David S. Siscovick, MD, MPH, João A.C. Lima, MD{ddagger}{ddagger} and Michael H. Criqui, MD, MPH{dagger}

* Division of Nephrology and Hypertension, Department of Medicine, University of California San Diego, San Diego, California
{dagger} Division of Preventive Medicine, Department of Family and Preventive Medicine, University of California San Diego, San Diego, California
{ddagger} Nephrology Section, Veterans Affairs San Diego Healthcare System, San Diego, California
§ Collaborative Health Studies Coordinating Center, Department of Biostatistics, University of Washington, Seattle, Washington
|| Division of Nephrology, Department of Medicine, University of Washington, Seattle, Washington
Cardiovascular Health Research Unit, Departments of Medicine and Epidemiology, University of Washington, Seattle, Washington
# Division of Nephrology, Department of Medicine, University of California San Francisco, San Francisco, California
** San Francisco Veterans Affairs Medical Center, San Francisco, California
{dagger}{dagger} Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, Maryland
{ddagger}{ddagger} Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, Maryland


Figure 1
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Figure 1 Association of the Spectrum of Ankle Brachial Index With Left Ventricular Mass, With Adjustment for Demographic Data, Traditional Cardiovascular Disease Risk Factors, and Subclinical Atherosclerosis

Model 1: adjusted for age, sex, race/ethnicity, and field center site. Model 2: adjusted for Model 1 variables and hypertension, diabetes, smoking, systolic blood pressure, total cholesterol, low-density lipoprotein cholesterol, natural log-transformed (C-reactive protein), estimated glomerular filtration rate, natural log-transformed (urine albumin/creatinine). Model 3: adjusted for Model 2 variables and common carotid intima media thickness (cIMT), internal cIMT, and natural log-transformed coronary artery calcification.

 

Figure 2
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Figure 2 Association of the Spectrum of Ankle Blood Pressure With Left Ventricular Mass, With Adjustment for Brachial Blood Pressure and Demographic Data, Traditional Cardiovascular Disease Risk Factors, and Subclinical Atherosclerosis

Model 1: adjusted for brachial systolic blood pressure, age, sex, race/ethnicity, and field center site. Model 2: adjusted for Model 1 variables and hypertension, diabetes, smoking, total cholesterol, low-density lipoprotein cholesterol, natural log-transformed (C-reactive protein), estimated glomerular filtration rate, natural log-transformed (urine albumin/creatinine). Model 3: adjusted for Model 2 variables and common carotid intima media thickness (cIMT), internal cIMT, and natural log-transformed coronary artery calcification.

 




 
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