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Beyond Low-Density Lipoprotein Cholesterol

Respective Contributions of Non–High-Density Lipoprotein Cholesterol Levels, Triglycerides, and the Total Cholesterol/High-Density Lipoprotein Cholesterol Ratio to Coronary Heart Disease Risk in Apparently Healthy Men and Women

Benoit J. Arsenault, PhD^_*,, Jamal S. Rana, MD, PhD, Erik S.G. Stroes, MD, PhD^||, Jean-Pierre Després, PhD^_*,, Prediman K. Shah, MD, John J.P. Kastelein, MD, PhD^||, Nicholas J. Wareham, MBBS, PhD^#, S. Matthijs Boekholdt, MD, PhD^¶,_* and Kay-Tee Khaw, MBBChir^_**

^_* Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec, Québec, Canada
Departments of Anatomy and Physiology, Faculty of Medicine, Université Laval, Québec, Québec, Canada
Division of Kinesiology, Department of Social and Preventive Medicine, Université Laval, Québec, Québec, Canada
Cedars-Sinai Heart Center, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California
^|| Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands
^¶ Department of Cardiology, Academic Medical Center, Amsterdam, the Netherlands
^# Medical Research Council Epidemiology Unit, Institute of Public Health, University of Cambridge, Cambridge, United Kingdom
^_** Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Cambridge, United Kingdom

View larger version (18K): [in this window] [in a new window] [Download PPT slide]   Figure 1 Kaplan-Meier Survival Curves of Participants Classified Into Subgroups According to Median Lipid Levels Kaplan-Meier survival curves of participants classified into subgroups according to median lipid levels: (A) low-density lipoprotein cholesterol (LDL-C) (< or 150.6 mg/dl) and non–high-density lipoprotein cholesterol (HDL-C) levels (< or 177.6 mg/dl), (B) LDL-C (< or 150.6 mg/dl) and triglyceride (TG) levels (< or 128.3 mg/dl), and (C) LDL-C levels (< or 150.6 mg/dl) and the total cholesterol (TC) to HDL-C ratio (< or 4.42).