Impact of Heart Rate on Central Aortic Pressures and HemodynamicsAnalysis From the CAFE (Conduit Artery Function Evaluation) Study: CAFE-Heart Rate
Bryan Williams, MD*,
Peter S. Lacy, PhD for the CAFE and the ASCOT (Anglo-Scandinavian Cardiac Outcomes Trial) Investigators
Department of Cardiovascular Sciences, University of Leicester School of Medicine, and the Leicester NIHR Cardiovascular Biomedical Research Unit, Leicester, United Kingdom

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Figure 1 Relationship Between HR and Brachial or Central Pressures (Mean ± SD)
(A) Relationship between brachial (red circles) and central aortic (blue circles) systolic blood pressure and heart rate (HR). (B) Relationship between brachial (red circles) and central aortic (blue circles) pulse pressure and HR. Data are grouped into 10 beats/min heart rate increments (mean ± SD).
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Figure 2 Relationship Between HR and the Difference Between Brachial and Central Pressures
Relationship between heart rate (HR) and the difference between brachial and central systolic blood pressure (SBP) (A) or brachial and central pulse pressure (PP) (B).
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Figure 3 Relationship Between HR and Outgoing or Reflected Pressure Wave Components
(A) Relationship between heart rate (HR) and the outgoing pressure wave (P1 height, red circles) and HR and the reflected pressure wave (augmentation, blue circles). (B) Relationship between augmentation index (AIx) and HR.
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