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J Am Coll Cardiol, 2009; 54:269-276, doi:10.1016/j.jacc.2009.05.016 (Published online 17 June 2009).
© 2009 by the American College of Cardiology Foundation
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The Everolimus-Eluting Stent in Real-World Patients

6-Month Follow-Up of the X-SEARCH (Xience V Stent Evaluated at Rotterdam Cardiac Hospital) Registry

Yoshinobu Onuma, MD, Neville Kukreja, MA, MRCP, Nicolo Piazza, MD, Jannet Eindhoven, MSc, Chrysafios Girasis, MD, Lisanne Schenkeveld, MSc, Ron van Domburg, PhD, Patrick W. Serruys, MD, PhD* Interventional Cardiologists of the Thoraxcenter (2000 to 2007)

Thoraxcenter, Erasmus Medical Center, Rotterdam, the Netherlands


Figure 1
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Figure 1 Flowchart of Patient Selection

The flowchart represents patient inclusion and exclusion in the X-SEARCH (Xience Stent Evaluated At Rotterdam Cardiology Hospital) registry. *Occurring in the short transitional period (2 weeks) between paclitaxel-eluting stent/everolimus-eluting stent. BMS = bare-metal stent(s); DES = drug-eluting stent(s); PCI = percutaneous coronary intervention.

 

Figure 2
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Figure 2 Inclusion Periods of X-SEARCH and Historical Cohorts

Chronological order of 4 cohorts included in analysis: BMS, everolimus-eluting stent (EES), paclitaxel-eluting stent (PES), and SES. X-SEARCH = Xience Stent Evaluated At Rotterdam Cardiology Hospital; other abbreviations as in Figure 1.

 

Figure 3
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Figure 3 Unadjusted Survival Curves

Kaplan-Meier survival curves stratified according to the stent types: (A) all-cause death; (B) the composite of death or myocardial infarction; (C) target vessel revascularization; and (D) the composite of major adverse cardiac events (all-cause mortality, any myocardial infarction, or target vessel revascularization). BMS (black lines); EES (green lines); PES (yellow lines); SES (red lines). Abbreviations as in Figures 1 and 2.

 

Figure 4
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Figure 4 Adjusted Survival Curves

Adjusted survival curves stratified according to the stent types using Cox proportional hazard model: (A) all-cause death; (B) the composite of death or myocardial infarction; (C) target vessel revascularization; and (D) the composite of major adverse cardiac events (all-cause mortality, any myocardial infarction, or target vessel revascularization). BMS (black lines); EES (green lines); PES (yellow lines); SES (red lines). Abbreviations as in Figures 1 and 2.

 




 
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