The Everolimus-Eluting Stent in Real-World Patients6-Month Follow-Up of the X-SEARCH (Xience V Stent Evaluated at Rotterdam Cardiac Hospital) Registry
Yoshinobu Onuma, MD,
Neville Kukreja, MA, MRCP,
Nicolo Piazza, MD,
Jannet Eindhoven, MSc,
Chrysafios Girasis, MD,
Lisanne Schenkeveld, MSc,
Ron van Domburg, PhD,
Patrick W. Serruys, MD, PhD* Interventional Cardiologists of the Thoraxcenter (2000 to 2007)
Thoraxcenter, Erasmus Medical Center, Rotterdam, the Netherlands

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Figure 1 Flowchart of Patient Selection
The flowchart represents patient inclusion and exclusion in the X-SEARCH (Xience Stent Evaluated At Rotterdam Cardiology Hospital) registry. *Occurring in the short transitional period (2 weeks) between paclitaxel-eluting stent/everolimus-eluting stent. BMS = bare-metal stent(s); DES = drug-eluting stent(s); PCI = percutaneous coronary intervention.
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Figure 2 Inclusion Periods of X-SEARCH and Historical Cohorts
Chronological order of 4 cohorts included in analysis: BMS, everolimus-eluting stent (EES), paclitaxel-eluting stent (PES), and SES. X-SEARCH = Xience Stent Evaluated At Rotterdam Cardiology Hospital; other abbreviations as in Figure 1.
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Figure 3 Unadjusted Survival Curves
Kaplan-Meier survival curves stratified according to the stent types: (A) all-cause death; (B) the composite of death or myocardial infarction; (C) target vessel revascularization; and (D) the composite of major adverse cardiac events (all-cause mortality, any myocardial infarction, or target vessel revascularization). BMS (black lines); EES (green lines); PES (yellow lines); SES (red lines). Abbreviations as in Figures 1 and 2.
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Figure 4 Adjusted Survival Curves
Adjusted survival curves stratified according to the stent types using Cox proportional hazard model: (A) all-cause death; (B) the composite of death or myocardial infarction; (C) target vessel revascularization; and (D) the composite of major adverse cardiac events (all-cause mortality, any myocardial infarction, or target vessel revascularization). BMS (black lines); EES (green lines); PES (yellow lines); SES (red lines). Abbreviations as in Figures 1 and 2.
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