Atrial Fibrillation at Baseline and During Follow-Up in ALLHAT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial)
L. Julian Haywood, MD*,
Charles E. Ford, PhD ,*,
Richard S. Crow, MD ,
Barry R. Davis, MD, PhD ,
Barry M. Massie, MD ,
Paula T. Einhorn, MD||,
Angela Williard, RN, BSN¶ for the ALLHAT Collaborative Research Group
* Los Angeles County/University of Southern California Medical Center, Los Angeles, California
University of Texas Health Science Center at Houston, School of Public Health, Houston, Texas
University of Minnesota, Minneapolis, Minnesota
San Francisco Veterans Affairs Medical Center, San Francisco, California
|| Division of Prevention and Population Sciences, National Heart, Lung, and Blood Institute, Bethesda, Maryland
¶ Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana

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Figure 1 Kaplan-Meier Event Curves for All-Cause Mortality, CHD, Stroke, and HF
Kaplan-Meier event curves for all-cause mortality, coronary heart disease (CHD), stroke, and heart failure (HF) among chlorthalidone, amiodipine, and lisinopril participants with atrial fibrillation (AF) or atrial flutter (AFL) at trial entry (n = 334) compared with those without AF/AFL (n = 30,370). CI = confidence interval; MI = myocardial infarction; RR = relative risk (hazard ratio).
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Figure 2 Kaplan-Meier Cumulative Event Curves for All-Cause Mortality
Kaplan-Meier cumulative event curves for all-cause mortality in chlorthalidone, amiodipine, and lisinopril participants with AF/AFL at trial entry or occurring during follow-up (n = 821) compared with mortality in those without AF/AFL (n = 27,247). In this time-dependent analysis, participants without AF/AFL at baseline remained in the AF/AFL absent risk group until new-onset AF/AFL was ascertained, at which time they were reclassified as AF/AFL present. Participants who died before a follow-up electrocardiogram could be obtained were classified as AF/AFL absent. Abbreviations as in Figure 1.
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