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J Am Coll Cardiol, 2009; 54:2023-2031, doi:10.1016/j.jacc.2009.08.020
© 2009 by the American College of Cardiology Foundation
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Atrial Fibrillation at Baseline and During Follow-Up in ALLHAT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial)

L. Julian Haywood, MD*, Charles E. Ford, PhD{dagger},*, Richard S. Crow, MD{ddagger}, Barry R. Davis, MD, PhD{dagger}, Barry M. Massie, MD§, Paula T. Einhorn, MD||, Angela Williard, RN, BSN for the ALLHAT Collaborative Research Group

* Los Angeles County/University of Southern California Medical Center, Los Angeles, California
{dagger} University of Texas Health Science Center at Houston, School of Public Health, Houston, Texas
{ddagger} University of Minnesota, Minneapolis, Minnesota
§ San Francisco Veterans Affairs Medical Center, San Francisco, California
|| Division of Prevention and Population Sciences, National Heart, Lung, and Blood Institute, Bethesda, Maryland
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana


Figure 1
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Figure 1 Kaplan-Meier Event Curves for All-Cause Mortality, CHD, Stroke, and HF

Kaplan-Meier event curves for all-cause mortality, coronary heart disease (CHD), stroke, and heart failure (HF) among chlorthalidone, amiodipine, and lisinopril participants with atrial fibrillation (AF) or atrial flutter (AFL) at trial entry (n = 334) compared with those without AF/AFL (n = 30,370). CI = confidence interval; MI = myocardial infarction; RR = relative risk (hazard ratio).

 

Figure 2
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Figure 2 Kaplan-Meier Cumulative Event Curves for All-Cause Mortality

Kaplan-Meier cumulative event curves for all-cause mortality in chlorthalidone, amiodipine, and lisinopril participants with AF/AFL at trial entry or occurring during follow-up (n = 821) compared with mortality in those without AF/AFL (n = 27,247). In this time-dependent analysis, participants without AF/AFL at baseline remained in the AF/AFL absent risk group until new-onset AF/AFL was ascertained, at which time they were reclassified as AF/AFL present. Participants who died before a follow-up electrocardiogram could be obtained were classified as AF/AFL absent. Abbreviations as in Figure 1.

 




 
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