Survival Implication of Left Ventricular End-Systolic Diameter in Mitral Regurgitation Due to Flail LeafletsA Long-Term Follow-Up Multicenter Study
Christophe Tribouilloy, MD, PhD*,*,
Francesco Grigioni, MD, PhD ,
Jean François Avierinos, MD ,
Andrea Barbieri, MD ,
Dan Rusinaru, MD*,
Catherine Szymanski, MD*,
Marinella Ferlito, MD ,
Laurence Tafanelli, MD ,
Francesca Bursi, MD ,
Faouzi Trojette, MD*,
Angelo Branzi, MD ,
Gilbert Habib, MD ,
Maria G. Modena, MD ,
Maurice Enriquez-Sarano, MD|| on behalf of the MIDA Investigators
* Department of Cardiology, INSERM, ERI 12, and University Hospital, Amiens, France
Cardiovascular Department, University Hospital of Bologna, Bologna, Italy
Department of Cardiology, University Hospital of Marseille, Marseille, France
Department of Cardiology, University Hospital of Modena, Modena, Italy
|| Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota

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Figure 1 Overall Survival According to LVESD in Patients With Organic MR
Overall survival according to left ventricular end-systolic diameter (LVESD) in patients with organic mitral regurgitation (MR): (A) conservative management (B) medical and surgical treatment.
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Figure 2 Association Between LVESD and the Risk of Overall Mortality Under Conservative Management
Hazard ratio (solid line) and 95% confidence intervals were estimated in a Cox multivariable model with left ventricular end-systolic diameter (LVESD) represented as a spline function.
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Figure 3 Survival Free of Cardiac Death According to LVESD in Patients With Organic MR
Survival free of cardiac death according to LVESD in patients with organic MR: (A) conservative management (B) medical and surgical treatment. Abbreviations as in Figure 1.
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Figure 4 Adjusted Post-Operative Overall Survival According to LVESD in Operated Patients With Organic MR
Adjusted post-operative overall survival according to LVESD in operated patients with organic MR. Abbreviations as in Figure 1.
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