High Central Pulse Pressure Is Independently Associated With Adverse Cardiovascular OutcomeThe Strong Heart Study
Mary J. Roman, MD*,*,
Richard B. Devereux, MD*,
Jorge R. Kizer, MD, MSc*,
Peter M. Okin, MD*,
Elisa T. Lee, PhD ,
Wenyu Wang, PhD,
Jason G. Umans, MD, PhD ,
Darren Calhoun, PhD and
Barbara V. Howard, PhD
* Division of Cardiology, Weill Cornell Medical College, New York, New York
Center for American Indian Health Research, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Medstar Research Institute, Washington, DC
View larger version (21K):
[in this window]
[in a new window]
[Download PPT slide]
|
Figure 1 Hazards Ratios for Incident Cardiovascular Event
Hazards ratios for incident cardiovascular events in 2,405 individuals initially free of clinical cardiovascular disease are stratified by quartiles of brachial (hatched bars) and central aortic (solid bars) pulse pressures (PPs). Quartiles of central PP (p < 0.001) predicted outcome more strongly than quartiles of brachial PP (p = 0.052). Only the event rate in the fourth central PP quartile (PP  50 mm Hg) was significantly higher than in the first quartile (p = 0.003).
|
|
View larger version (16K):
[in this window]
[in a new window]
[Download PPT slide]
|
Figure 2 Box Plots of Brachial PP per Quartile of Central Aortic PP
Box plots (median, quartiles, and range) of brachial pulse pressure (PP) stratified by quartile of central aortic PP demonstrate substantial overlap of brachial PP values across quartiles and highlight the inability to accurately estimate central pressure from brachial pressure.
|
|
|
