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J Am Coll Cardiol, 2009; 54:1500-1511, doi:10.1016/j.jacc.2009.07.007 (Published online 19 August 2009).
© 2009 by the American College of Cardiology Foundation
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Early and Long-Term Results of Unprotected Left Main Coronary Artery Stenting

The LE MANS (Left Main Coronary Artery Stenting) Registry

Pawel E. Buszman, MD*,{dagger},{ddagger},*, Piotr P. Buszman, MD*,{ddagger}, R. Stefan Kiesz, MD§, Andrzej Bochenek, MD*,{dagger}, Blazej Trela, MD*, Magda Konkolewska, MD*, David Wallace-Bradley, BS||, Miroslaw Wilczynski, MD{dagger}, Iwona Banasiewicz-Szkróbka, MD{dagger}, Ewa Peszek-Przybyla, MD{dagger}, Marek Krol, MD{ddagger}, Marek Kondys, MD, Krzysztof Milewski, MD{dagger},||, Szymon Wiernek, MD*,§, Marcin Debinski, MD{dagger}, Aleksander Zurakowski, MD{dagger}, Jack L. Martin, MD§,# and Michal Tendera, MD*,{dagger}

* Medical University of Silesia, Katowice, Poland
{dagger} Upper-Silesian Heart Centre, Katowice, Poland
{ddagger} American Heart of Poland, Ustron, Poland
§ San Antonio Endovascular and Heart Institute and University of Texas Health Science Center at San Antonio, San Antonio, Texas
|| Cardiovascular Research Foundation, New York, New York
American Heart of Poland, Dabrowa Gornicza, Poland
# Thomas Jefferson University, Philadelphia, Pennsylvania


Figure 1
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  		Figure 1 The LE MANS Study Algorithm

The LE MANS algorithm is from Buszman et al. (24) but is based on new data. BMS = bare-metal stent(s); CABG = coronary artery bypass grafting; DES = drug-eluting stent(s); LMCA = left main coronary artery; PCI = percutaneous coronary intervention; STEMI = ST-segment elevation myocardial infarction.

 

Figure 2
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  		Figure 2 Early and Long-Term Results for the Whole Study Group

(A) Mortality and major adverse cardiovascular and cerebral events (MACCE) at 30-day and long-term follow-up. (B) The incidence of MACCE, myocardial infarction (MI), stroke, and target lesion revascularization (TLR) at long-term follow-up.

 

Figure 3
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  		Figure 3 Kaplan-Meier Survival Curves

(A) Survival and major adverse cardiovascular and cerebral event-free (MACCE) survival curves for the whole study group. (B) Survival in subgroups with isolated left main (LM) and LM with 1-, 2-, and 3-vessel disease (VD).

 

Figure 4
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  		Figure 4 Long-Term Unadjusted DES Versus BMS Results

Mortality and MACCE in DES and BMS groups. Abbreviations as in Figures 1 and 2.

 

Figure 5
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  		Figure 5 Long-Term Adjusted DES Versus BMS Results

Survival (A) and MACCE-free survival (B) in BMS and DES cohorts. Abbreviations as in Figures 1 and 2.

 

Figure 6
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  		Figure 6 Long-Term Adjusted DES Versus BMS Results, Continued

MI-free survival (A) and TLR-free survival (B) in BMS and DES cohorts. Abbreviations as in Figures 1 and 2.

 

Figure 7
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  		Figure 7 Patient Cohorts With Distal Versus Proximal/Medial LM Involvement

(A) Survival and (B) MACCE-free survival. LM = left main coronary artery; med = medial; prox = proximal; other abbreviations as in Figures 1 and 2.

 

Figure 8
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  		Figure 8 Distal Left Main Cohort

(A) DES versus BMS survival. (B) The MACCE-free survival. Abbreviations as in Figures 1 and 2.

 
 
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