Comparison of Omeprazole and Pantoprazole Influence on a High 150-mg Clopidogrel Maintenance DoseThe PACA (Proton Pump Inhibitors And Clopidogrel Association) Prospective Randomized Study
Thomas Cuisset, MD*, , ,*,
Corinne Frere, MD,,
Jacques Quilici, MD*,
Raphael Poyet, MD*,
Bénédicte Gaborit, MD,,
Laurent Bali, MD*,
Olivier Brissy, MD*,
Pierre-Emmanuel Morange, MD, PhD,,
Marie-Christine Alessi, MD, PhD, and
Jean-Louis Bonnet, MD*
* Département de Cardiologie, CHU Timone, Marseille, France
Laboratoire d'Hématologie, CHU Timone, Marseille, France
INSERM, UMR 626, Faculté de Médecine, Marseille, France
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Figure 2 Platelet Parameters and According to Proton Pump Inhibitors
Clopidogrel response with platelet reactivity index vasoactive stimulated phosphoprotein (PRI VASP) (A) and platelet reactivity with adenosine diphosphate–induced platelet aggregation (ADP-Ag) (B) according to proton pump inhibitor treatment.
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Figure 3 Prevalence of Clopidogrel Nonresponders
Prevalence of clopidogrel nonresponders (platelet reactivity index vasoactive stimulated phosphoprotein >50%) according to proton pump inhibitor treatment.
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