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J Am Coll Cardiol, 2009; 54:894-902, doi:10.1016/j.jacc.2009.04.077
© 2009 by the American College of Cardiology Foundation
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5-Year Clinical Outcomes After Sirolimus-Eluting Stent Implantation

Insights From a Patient-Level Pooled Analysis of 4 Randomized Trials Comparing Sirolimus-Eluting Stents With Bare-Metal Stents

Adriano Caixeta, MD, PhD*, Martin B. Leon, MD*, Alexandra J. Lansky, MD*, Eugenia Nikolsky, MD, PhD*, Jiro Aoki, MD, PhD*, Jeffrey W. Moses, MD*, Joachim Schofer, MD{dagger}, Marie-Claude Morice, MD{ddagger}, Erick Schampaert, MD§, Ajay J. Kirtane, MD, SM*, Jeffrey J. Popma, MD||, Helen Parise, DSc*, Martin Fahy, MSc* and Roxana Mehran, MD*,*

* Columbia University Medical Center and the Cardiovascular Research Foundation, New York, New York
{dagger} Hamburg University Cardiovascular Center, Hamburg, Germany
{ddagger} Institut Cardiovasculaire Paris Sud, Massy, France
§ Hôpital du Sacre-Coeur de Montréal, Montréal, Quebec, Canada
|| St. Elisabeth Medical Center, Boston, Massachusetts


Figure 1
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Figure 1 Kaplan-Meier Event Curves for Patients Treated With SES or BMS

Five-year cumulative event curves for (A) death, (B) death or myocardial infarction (MI), and (C) target vessel revascularization (TVR). BMS = bare-metal stent(s); SES = sirolimus-eluting stent(s).

 

Figure 2
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Figure 2 Kaplan-Meier Curves for Patients With Stent Thrombosis as Defined by the ARC

Five-year cumulative event curves for (A) any stent thrombosis, (B) definite stent thrombosis, and (C) definite and probable stent thrombosis. ARC = Academic Research Consortium; other abbreviations as in Figure 1.

 

Figure 3
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Figure 3 Kaplan-Meier Event Curves With Landmark Analysis From 4- to 5-Year Follow-Up

Landmark analyses of (A) cardiac death, (B) cardiac death or MI, and (C) definite and probable stent thrombosis. Abbreviations as in Figures 1 and 2.

 

Figure 4
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Figure 4 Kaplan-Meier Event Curves for Patients With and Without Diabetes

Five-year cumulative event curves for (A) death and (B) death or MI for patients with diabetes, and cumulative event curves for (C) death and (D) death or MI for patients without diabetes. Abbreviations as in Figure 1.

 




 
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