Proof of ConceptHemodynamic Response to Long-Term Partial Ventricular Support With the Synergy Pocket Micro-Pump
Bart Meyns, MD, PhD*,
Stefan Klotz, MD, PhD ,
Andre Simon, MD ,
Walter Droogne, MD*,
Filip Rega, MD*,
Bartley Griffith, MD ,
Robert Dowling, MD||,
Mark J. Zucker, MD¶ and
Daniel Burkhoff, MD, PhD#,**,*
* University of Leuven, Leuven, Belgium
University of Münster, Münster, Germany
Hannover Medical School, Hannover, Germany
University of Maryland, Baltimore, Maryland
|| Univeristy of Louisville, Louisville, Kentucky
¶ Newark Beth Israel Medical Center, Newark, New Jersey
# CircuLite, Inc., Saddle Brook, New Jersey
** Columbia University, New York, New York
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Figure 2 Plasma-Free Hemoglobin Over Time
Plasma-free hemoglobin values obtained during the first 4 weeks of support show that there is minimal hemolysis during use of the Synergy Micro-pump.
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Figure 3 Hemodynamics Over Time
Hemodynamic parameters from 9 patients (with mean and SD) who returned for follow-up right heart catheterization a mean of 10 ± 6 weeks after implantation. The p values are for comparison between baseline and chronic follow-up. Red lines are individual patients; blue lines are group averages. PA = pulmonary artery.
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Figure 4 Cannula Tips at Time of Heart Transplant
Pictures of the tip of the inflow cannula taken from the left atrium of 3 patients obtained at the time of heart transplant. The cannula is well healed.
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Figure 5 Rotor Images at Time of Explant
Pictures of the rotor after the specified number of days of support showing that the rotor is free of thrombus and remnants of cellular debris.
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