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J Am Coll Cardiol, 2008; 52:569-576, doi:10.1016/j.jacc.2008.04.049
© 2008 by the American College of Cardiology Foundation
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Endothelial Function in Human Immunodeficiency Virus-Infected Antiretroviral-Naive Subjects Before and After Starting Potent Antiretroviral Therapy

The ACTG (AIDS Clinical Trials Group) Study 5152s

Francesca J. Torriani, MD*,*, Lauren Komarow, MS{dagger}, Robert A. Parker, ScD{dagger}, Bruno R. Cotter, MD, FACC*, Judith S. Currier, MD{ddagger}, Michael P. Dubé, MD§, Carl J. Fichtenbaum, MD||, Mariana Gerschenson, PhD, Carol K.C. Mitchell, PhD#, Robert L. Murphy, MD**, Kathleen Squires, MD{dagger}{dagger}, James H. Stein, MD, FACC# for the ACTG 5152s Study Team

* University of California–San Diego, San Diego, California
{dagger} Harvard School of Public Health, Boston, Massachusetts
{ddagger} University of California–Los Angeles, Los Angeles, California
§ Indiana University School of Medicine, Indianapolis, Indiana
|| University of Cincinnati Medical Center, Cincinnati, Ohio
University of Hawaii, Honolulu, Hawaii
# University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin
** Northwestern University Feinberg School of Medicine, Chicago, Illinois
{dagger}{dagger} University of Southern California, Los Angeles, California.


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Figure 1 Changes in Brachial Artery Flow-Mediated Dilation From Baseline to Week 24

Thick bars = medians; box edges = 25th and 75th percentiles; error bars = 95% confidence intervals. EFV = efavirenz; FMD = flow-mediated dilation; LPV/r = lopinavir/ritonavir; NNRTI = non-nucleoside reverse transcriptase inhibitor; NRTI = nucleoside reverse transcriptase inhibitor; PI = protease inhibitor. *p ≤ 0.005, #p = 0.015 within arm, compared with baseline (between groups, p = 0.828).

 




 
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