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No Benefit From Defibrillation Threshold Testing in the SCD-HeFT (Sudden Cardiac Death in Heart Failure Trial)

Joseph A. Blatt, MD^_*,_*, Jeanne E. Poole, MD^_*, George W. Johnson, BSEE, David J. Callans, MD, Merritt H. Raitt, MD, Ramakota K. Reddy, MD^||, Francis E. Marchlinski, MD, Raymond Yee, MD^¶, Thomas Guarnieri, MD^#, Mario Talajic, MD^_**, David J. Wilber, MD, Jill Anderson, RN, Kiyon Chung, MD, MPH, Wai Shun Wong, MD, Daniel B. Mark, MD^||||, Kerry L. Lee, PhD^||||, Gust H. Bardy, MD^_*, for the SCD-HeFT Investigators

^_* University of Washington, Seattle, Washington
Seattle Institute for Cardiac Research, Seattle, Washington
The University of Pennsylvania, Philadelphia, Pennsylvania
Portland Veterans Affairs Medical Center, Portland, Oregon
^|| Oregon Cardiology, P.C., Eugene, Oregon
^¶ University of Western Ontario, London, Ontario, Canada
^# John Hopkins University, Baltimore, Maryland
^_** Montreal Heart Institute, Montreal, Quebec, Canada
Loyola University Health System, Maywood, Illinois
The Everett Clinic, Everett, Washington
University of Michigan, Ann Arbor, Michigan
^|||| Duke University School of Medicine, Durham, North Carolina.

View larger version (12K): [in this window] [in a new window] [Download PPT slide]   Figure 1 Histogram of Baseline DFT Data at the Time of ICD Implantation DFT = defibrillation threshold; ICD = implantable cardioverter-defibrillator.

View larger version (14K): [in this window] [in a new window] [Download PPT slide]   Figure 2 Kaplan-Meier Survival Curves Curves show no difference in all-cause mortality when patients with an ICD were divided by high-DFT and low-DFT groups (hazard ratio for DFT >10: 1.19; 95% confidence interval: 0.72 to 1.58; p = 0.41). Abbreviations as in Figure 1.