The Effects of Medications on Myocardial Perfusion
Gilbert J. Zoghbi, MD, FACC,
Todd A. Dorfman, MD* and
Ami E. Iskandrian, MD, MACC
Division of Cardiovascular Diseases, Department of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama.
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Figure 1 Baseline and Follow-Up Stress/Rest SPECT Sestamibi MPI After Medical Therapy
(A) A patient's baseline stress/rest SPECT sestamibi perfusion images showing large ischemia of the left anterior descending artery territory; the top rows show stress images and the bottom rows show rest images. (B) Polar maps estimated the extent of total ischemia to be 31% of left ventricular myocardium. The left ventricular ejection fraction was 62% by gated SPECT. (C) SPECT sestamibi MPI at 6-month follow-up with maximal medical therapy including statin, beta-blockers, and nitrates. The ischemia (same format as A) is less. (D) Polar maps estimated extent of total abnormality to be 21%, ischemia 16%, and scar 5%. The left ventricular ejection fraction was 67%. HLA = horizontal long axis; MPI = myocardial perfusion imaging; SAX = short axis; SPECT = single-photon emission computed tomography; VLA = vertical long axis.
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