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Influence of Beta-Blocker Continuation or Withdrawal on Outcomes in Patients Hospitalized With Heart Failure

Findings From the OPTIMIZE-HF Program

Gregg C. Fonarow, MD, FACC^_*,_*, William T. Abraham, MD, FACP, FACC, Nancy M. Albert, PhD, RN, Wendy Gattis Stough, PharmD, Mihai Gheorghiade, MD^||, Barry H. Greenberg, MD, FACC^¶, Christopher M. O'Connor, MD, FACC^#, Jie Lena Sun, MS^_**, Clyde W. Yancy, MD, FACC, James B. Young, MD, FACC on behalf of the OPTIMIZE-HF Investigators and Coordinators

^_* Department of Medicine, University of California–Los Angeles Medical Center, Los Angeles, California
Division of Cardiology, The Ohio State University, Columbus, Ohio
George M. and Linda H. Kaufman Center for Heart Failure, Cleveland Clinic Foundation, Cleveland, Ohio
Department of Medicine, Duke University Medical Center, Durham, North Carolina, and Department of Clinical Research, Campbell University School of Pharmacy, Research Triangle Park, North Carolina
^|| Division of Cardiology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois
^¶ Department of Medicine, USCD Medical Center, University of California, San Diego, California
^# Division of Cardiology, Duke University Medical Center/Duke Clinical Research Institute, Durham, North Carolina
^_** Duke Clinical Research Institute, Durham, North Carolina
Baylor University Medical Center, Dallas, Texas
Department of Cardiovascular Medicine, Heart Failure Section, Cleveland Clinic Foundation, Cleveland, Ohio.

View larger version (18K): [in this window] [in a new window] [Download PPT slide]   Figure 1 Post-Discharge Survival by Beta-Blocker Treatment Groups Kaplan-Meier survival curves by beta-blocker treatment groups. Log-rank test: p < 0.001.