Myocardial Steatosis Is an Independent Predictor of Diastolic Dysfunction in Type 2 Diabetes Mellitus
Luuk J. Rijzewijk, MD*,
Rutger W. van der Meer, MD ,*,
Johannes W.A. Smit, MD, PhD ,
Michaela Diamant, MD, PhD*,
Jeroen J. Bax, MD, PhD ,
Sebastiaan Hammer, MSc,
Johannes A. Romijn, MD, PhD,
Albert de Roos, MD, PhD and
Hildo J. Lamb, MD, PhD,*
* Department of Endocrinology, VU University Medical Center, Amsterdam, the Netherlands
Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands
Department of Endocrinology, Leiden University Medical Center, Leiden, the Netherlands
Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands
View larger version (5K):
[in this window]
[in a new window]
[Download PPT slide]
|
Figure 1 Myocardial and Hepatic Triglyceride Content in Patients and Controls
Bar graphs show increased myocardial and hepatic triglyceride content in diabetic patients as compared with healthy control subjects. Bars represent mean ± standard error for myocardial triglycerides and median ± interquartile range for hepatic triglycerides. *p < 0.05.
|
|
View larger version (8K):
[in this window]
[in a new window]
[Download PPT slide]
|
Figure 2 Correlations Between Myocardial Triglyceride Content and Left Ventricular Diastolic Function
Increased myocardial triglyceride content is significantly associated with decreased myocardial function. E = early diastolic filling phase, E/A = ratio of maximal left ventricular early peak filling rate and the maximal left ventricular atrial peak filling rate.
|
|
|
