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Long-Term Clinical Benefit of Sirolimus-Eluting Stents in Patients With In-Stent Restenosis

Results of the RIBS-II (Restenosis Intra-stent: Balloon angioplasty vs. elective sirolimus-eluting Stenting) Study

Fernando Alfonso, MD^_*,_*, María-José Pérez-Vizcayno, MD^_*, Rosana Hernández, MD^_*, Armando Bethencourt, MD, Vicens Martí, MD, José R. López-Mínguez, MD, Juan Angel, MD^||, Andrés Iñiguez, MD^¶, César Morís, MD^#, Angel Cequier, MD^_**, Manel Sabaté, MD, Javier Escaned, MD^_*, Pilar Jiménez-Quevedo, MD^_*, Camino Bañuelos, MD^_*, Alfonso Suárez, MD^_*, Carlos Macaya, MD^_* for the RIBS-II Investigators

^_* University Hospital, Clinico San Carlos, Madrid, Spain
University Hospital, Son Dureta, Palma de Mallorca, Spain
University Hospital, San Pablo, Barcelona, Spain
University Hospital, Infanta Cristina, Badajoz, Spain
^|| University Hospital, Valle de Hebrón, Barcelona, Spain
^¶ University Hospital, Meixoeiro, Vigo, Spain
^# University Hospital, Central Asturias, Oviedo, Spain
^_** University Hospital, Bellvitge, Barcelona, Spain

View larger version (11K): [in this window] [in a new window] [Download PPT slide]   Figure 1 Kaplan-Meier Estimates of Event-Free Survival Kaplan-Meier estimates of event-free survival (death, myocardial infarction, and target vessel revascularization). Red line = sirolimus-eluting stent; blue line = balloon angioplasty.

View larger version (11K): [in this window] [in a new window] [Download PPT slide]   Figure 2 Long-Term Clinical Outcome According to 10 Pre-Specified Variables No patient with in-stent restenosis of a coil stent (1st ST Coil) was included. BA = balloon angioplasty; B/A = balloon-artery ratio; CI = confidence interval; LAD = left anterior descending coronary artery; RE = restenosis; SES = sirolimus-eluting stent.