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Does Microvolt T-Wave Alternans Testing Predict Ventricular Tachyarrhythmias in Patients With Ischemic Cardiomyopathy and Prophylactic Defibrillators?

The MASTER (Microvolt T Wave Alternans Testing for Risk Stratification of Post-Myocardial Infarction Patients) Trial

Theodore Chow, MD, FACC^_*,_*, Dean J. Kereiakes, MD, FACC^_*, John Onufer, MD, Alan Woelfel, MD, Sinan Gursoy, MD, Brett J. Peterson, BS^||, Mark L. Brown, PhD^||, Wenji Pu, PhD^||, David G. Benditt, MD^¶ on behalf of the MASTER Trial Investigators

^_* The Lindner Clinical Trial Center at The Christ Hospital, Cincinnati, Ohio
Cardiovascular Associates, Ltd., Chesapeake, Virginia
West Michigan Heart, Grand Rapids, Michigan
Naples Community Hospital, Naples, Florida
^|| Medtronic, Inc., Minneapolis, Minnesota
^¶ University of Minnesota, Minneapolis, Minnesota

View larger version (9K): [in this window] [in a new window] [Download PPT slide]   Figure 1 Kaplan-Meier Survival Curves for VTE Free Survival MTWA = microvolt T-wave alternans; VTE = ventricular tachyarrhythmic event (primary end point).

View larger version (9K): [in this window] [in a new window] [Download PPT slide]   Figure 2 Kaplan-Meier Survival Curves for Total Mortality MTWA = microvolt T-wave alternans.