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J Am Coll Cardiol, 2008; 52:108-113, doi:10.1016/j.jacc.2007.12.063
© 2008 by the American College of Cardiology Foundation
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Fontan Fenestration Closure Has No Acute Effect on Exercise Capacity but Improves Ventilatory Response to Exercise

Jeffery Meadows, MD*,*, Peter Lang, MD*,{dagger}, Gerald Marx, MD*,{dagger} and Jonathan Rhodes, MD*,{dagger}

* Department of Cardiology, Children's Hospital–Boston, Boston, Massachusetts
{dagger} Department of Pediatrics, Harvard Medical School, Boston, Massachusetts.


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  		Figure 1 Changes in Ventilatory Function During Exercise After Fenestration Closure

Fenestration closure-associated changes in each individual patient's minute ventilation/carbon dioxide elimination (VE/VCO2) slope (A), end-tidal partial pressure of carbon dioxide (pCO2) at the ventilatory anaerobic threshold (B), and end-tidal partial pressure of oxygen (pO2) at the anaerobic threshold (C). The VE/VCO2 slope fell in every patient. The end-tidal pCO2 rose and the end-tidal pO2 fell in 19 of 20 patients. Post = post-fenestration closure; Pre = pre-fenestration closure.

 
 
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