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Ethnicity and Left Ventricular Diastolic Function in Hypertension

An ASCOT (Anglo-Scandinavian Cardiac Outcomes Trial) Substudy

Andrew Sharp, MBChB^_*,_*, Robyn Tapp, PhD^_*,, Darrel P. Francis, MD^_*, Simon A. McG. Thom, MD^_*, Alun D. Hughes, MD, PhD^_*, Alice V. Stanton, MD, PhD, Andrew Zambanini, MD^_*, Nish Chaturvedi, MD^_*, Sheila Byrd, BSc^_*, Neil R. Poulter, MD^_*, Peter S. Sever, MD^_* and Jamil Mayet, MD^_*

^_* International Centre for Circulatory Health, St. Mary's Hospital and Imperial College London, London, United Kingdom
Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia
Department of Clinical Pharmacology, Royal College of Surgeons of Ireland, Dublin, Ireland

View larger version (23K): [in this window] [in a new window] [Download PPT slide]   Figure 1 Relationship of Age Group and Ethnicity to Diastolic Function, as Measured by E' and the E/E' Ratio The magnitude of the ethnic difference in these markers of diastolic function in comparison with that of each decade of aging is demonstrated. Diastolic function was assessed using the tissue Doppler early diastolic velocity (E') and the ratio of this and the transmitral early filling velocity (E/E').