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J Am Coll Cardiol, 2008; 52:17-23, doi:10.1016/j.jacc.2008.04.004
© 2008 by the American College of Cardiology Foundation
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Coronary Artery Calcium to Predict All-Cause Mortality in Elderly Men and Women

Paolo Raggi, MD*,{dagger},*, Maria C. Gongora, MD*, Ambarish Gopal, MD{ddagger}, Tracy Q. Callister, MD§, Matthew Budoff, MD{ddagger} and Leslee J. Shaw, PhD*

* Division of Cardiology and Department of Medicine, Emory University School of Medicine, Atlanta, Georgia
{dagger} Department of Radiology, Emory University School of Medicine, Atlanta, Georgia
{ddagger} Division of Cardiology and Department of Medicine, Harbor UCLA, University of California, Torrance, California
§ Tennessee Heart and Vascular Institute, Nashville, Tennessee.


Figure 1
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Figure 1 Unadjusted Survival by Gender

 

Figure 2
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Figure 2 Gender-Specific Mortality Rates

Unadjusted all-cause mortality rates by gender and age deciles at 4 to 6 years of follow-up.

 

Figure 3
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Figure 3 Gender-Specific Survival According to Calcium Score

Risk-adjusted survival by coronary artery calcium across age deciles in women and men.

 

Figure 4
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Figure 4 Risk of Death Without CAC

Annual mortality (left y-axis) in patients without CAC by age decile including hazard ratios (95% CIs; right y-axis) compared with patients <40 years. The hazard ratios are shown next to the bar graphs. CAC = coronary artery calcium; CI = confidence interval.

 

Figure 5
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Figure 5 Reclassification of Risk With the Use of Coronary Calcium Scoring

Percentage of patients reclassified based on coronary artery calcium (CAC) <400 or ≥400 (p < 0.0001 for women and men) beyond the Framingham risk score (FRS). With a high FRS, patients were reclassified if CAC <400. With a low-intermediate FRS, patients were reclassified if CAC ≥400. The numbers at the top of each column indicate the number of deaths identified beyond those defined by the FRS in each patient subset.

 




 
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