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Lipoprotein-Associated Phospholipase A2 Is an Independent Predictor of Incident Coronary Heart Disease in an Apparently Healthy Older Population

The Rancho Bernardo Study

Lori B. Daniels, MD^_*,_*, Gail A. Laughlin, PhD, Mark J. Sarno, BA, Ricki Bettencourt, MS, Robert L. Wolfert, PhD and Elizabeth Barrett-Connor, MD

^_* Division of Cardiology, Department of Medicine, University of California at San Diego, San Diego, California
Department of Family and Preventive Medicine, University of California at San Diego, La Jolla, California
diaDexus, Inc., South San Francisco, California.

View larger version (20K): [in this window] [in a new window] [Download PPT slide]   Figure 1 Age-Adjusted Event-Free Survival by Lp-PLA2 Tertile Age-adjusted survival free of fatal or nonfatal myocardial infarction, coronary revascularization, or angina, by lipoprotein-associated phospholipase A2 (Lp-PLA2) tertile (low 108.1 to 434.4 ng/ml; medium 434.4 to 574.2 ng/ml; high 574.3 to 3,126.8 ng/ml). CHD = coronary heart disease.