Evaluation and Long-Term Prognosis of New-Onset, Transient, and Persistent Anemia in Ambulatory Patients With Chronic Heart Failure
W.H. Wilson Tang, MD, FACC*,1,*,
Wilson Tong, MSc*,
Anil Jain, MD , ,
Gary S. Francis, MD, FACC*,1,
C. Martin Harris, MD, MBA and
James B. Young, MD, FACC*,1
* Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio
Department of Internal Medicine, Cleveland Clinic, Cleveland, Ohio
Information Technology Division, Cleveland Clinic, Cleveland, Ohio.

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Figure 1 Prevalence and Resolution of Anemia in the Study Population
This is a flow diagram describing subject selection according to anemia status in the total population (n = 6,159) as well as in the subgroup with follow-up hemoglobin levels (n = 1,393).
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Figure 2 Prevalence of Baseline Anemia Stratified by Age and Gender
Bar graph illustrating the prevalence of anemia according to age cohorts and differences in rates between men and women.
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Figure 3 Anemia Characteristics According to Patient Subgroups
Bar graphs illustrating rates of persistent, transient, incident, or no anemia according to subgroups above versus below median values, including (A) baseline estimated glomerular filtration rates (eGFR) (median 60 ml/min/1.73 m2); (B) baseline left ventricular ejection fraction (LVEF) (median 30%); (C) baseline B-type natriuretic peptide levels (BNP) (median 325 pg/ml); and (D) baseline diabetes status.
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Figure 4 Kaplan-Meier Analysis of All-Cause Mortality According to Anemia Status
Stratified according to (A) presence or absence of anemia at baseline and to (B) persistent, transient, incident, or no anemia at follow-up.
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