Relation Between Stress-Induced Myocardial Perfusion Defects on Cardiovascular Magnetic Resonance and Coronary Microvascular Dysfunction in Patients With Cardiac Syndrome X
Gaetano A. Lanza, MD*,*,
Antonino Buffon, MD*,
Alfonso Sestito, MD*,
Luigi Natale, MD ,
Gregory A. Sgueglia, MD*,
Leda Galiuto, MD, FACC*,
Fabio Infusino, MD*,
Luca Mariani, MD*,
Antonio Centola, MD* and
Filippo Crea, MD, FACC*
* Istituto di Cardiologia, Università Cattolica del Sacro Cuore, Rome, Italy
Istituto di Radiologia, Università Cattolica del Sacro Cuore, Rome, Italy.

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Figure 1 Coronary Flow Response to Adenosine in CSX Patients and Control Subjects
Individual and average (±SD) values of coronary blood flow response to adenosine in the left anterior descending (LAD) coronary artery, as assessed by transthoracic echo-Doppler, in cardiac syndrome X (CSX) patients and in healthy control subjects. The CSX patients are divided into those showing reversible perfusion defects (CSX LAD/CMR+) and those not showing any reversible regional perfusion defects (CSX LAD/CMR–) in the LAD territory on cardiovascular magnetic resonance (CMR) during dobutamine stress test.
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Figure 2 Myocardial Perfusion Defect on CMR During DST in a Patient With CSX
Cardiovascular perfusion magnetic resonance (CMR) first-pass study in a patient with cardiac syndrome X (CSX) (short-axis plane). In the left panels, obtained 26 s after administration of gadolinium at peak dobutamine stress test (DST), a perfusion defect is clearly visible in the mid-ventricular septum (arrows). The perfusion defect normalizes at rest (right).
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