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A Kinesin Family Member 6 Variant Is Associated With Coronary Heart Disease in the Women’s Health Study

Dov Shiffman, PhD^_*,1,2,_*, Daniel I. Chasman, PhD^,2, Robert Y.L. Zee, PhD^_*, Olga A. Iakoubova, MD, PhD^_*,1, Judy Z. Louie, BA^_*,1, James J. Devlin, PhD^_*,1 and Paul M. Ridker, MD^,

^_* Celera, Alameda, California
Division of Preventive Medicine, Center for Cardiovascular Disease Prevention, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts
Division of Cardiology, Center for Cardiovascular Disease Prevention, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts.

View larger version (12K): [in this window] [in a new window] [Download PPT slide]   Figure 1 Risk of CHD or MI Comparison of Kaplan-Meier estimates of the cumulative incidence of coronary heart disease (CHD) events and myocardial infarction (MI) events among carriers of the KIF6 719Arg allele and noncarriers. Log-rank p values are for mean follow-up time of 12 years.