Elevated Intra-Abdominal Pressure in Acute Decompensated Heart FailureA Potential Contributor to Worsening Renal Function?
Wilfried Mullens, MD*,
Zuheir Abrahams, MD, PhD*,
Hadi N. Skouri, MD*,
Gary S. Francis, MD, FACC*,
David O. Taylor, MD, FACC*,
Randall C. Starling, MD, MPH, FACC*,
Emil Paganini, MD and
W.H. Wilson Tang, MD, FACC*,*
* Section of Heart Failure and Cardiac Transplantation, the Cleveland Clinic, Cleveland, Ohio
Section of Nephrology and Hypertension, the Cleveland Clinic, Cleveland, Ohio.
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Figure 2 Change in IAP in Patients With Baseline Elevated Intra-Abdominal Pressure
Noted overall trend of reduction in intra-abdominal pressures (IAP) in patients with IAP at  8 mm Hg at baseline.
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Figure 3 Baseline Serum Creatinine Level and IAP
Box and whisker plot with median, quartiles, and extremes for serum creatinine levels for all patients with intra-abdominal pressure (IAP) <8 mm Hg and 8 mm Hg at baseline. Note that there is a statistically higher serum creatinine level in patients with a higher IAP.
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Figure 4 Changes in Renal Parameters and Changes in IAP
Relationship between changes in renal function and changes in intra-abdominal pressure (IAP) (A) and estimated renal filtration gradient (B) in patients with IAP 8 mm Hg at baseline.
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