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Clinical Utility of C-Reactive Protein Measured at Admission, Hospital Discharge, and 1 Month Later to Predict Outcome in Patients With Acute Coronary Disease

The RISCA (Recurrence and Inflammation in the Acute Coronary Syndromes) Study

Peter Bogaty, MD^_*,_*, Luce Boyer, RN^_*, Serge Simard, MSc^_*, Franz Dauwe, MD, Robert Dupuis, MD, Benoît Verret, MD, Thao Huynh, MD^||, Fernand Bertrand, BSc^_*, Gilles R. Dagenais, MD, FACC^_* and James M. Brophy, MD, PhD, FACC^¶

^_* Quebec Heart Institute/Laval Hospital, Laval University, Quebec City, Quebec, Canada
Complexe hospitalier de la Sagamie, Chicoutimi, Quebec, Canada
Centre hospitalier de la région de l'Amiante, Thetford-Mines, Quebec, Canada
Centre hospitalier régional du Grand-Portage, Rivière-du-Loup, Quebec, Canada
^|| Montreal General Hospital, McGill University Health Center, Montreal, Quebec, Canada
^¶ Hôpital Notre Dame, University of Montreal and McGill University Health Center, Montreal, Quebec, Canada.

View larger version (32K): [in this window] [in a new window] [Download PPT slide]   Figure 1 Selection of Study Cohort Flow diagram of screened patients admitted with chest pain, depicting reasons for exclusions in selection of study cohort. *Excludes any patients who died before they could be approached for this study. **In some centers.

View larger version (26K): [in this window] [in a new window] [Download PPT slide]   Figure 2 CRP Values in Patients With and Without Events The C-reactive protein (CRP) values at admission, at hospital discharge, and at 1 month after discharge in patients with and without occurrence of the primary outcome (death, myocardial infarction [MI] by troponin definition, or unstable angina [UA] with electrocardiographic changes) and its individual components.