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Novel Metabolic Risk Factors for Incident Heart Failure and Their Relationship With Obesity

The MESA (Multi-Ethnic Study of Atherosclerosis) Study

Hossein Bahrami, MD, MPH, PhD^_*,, David A. Bluemke, MD, PhD^_*,, Richard Kronmal, PhD^,||, Alain G. Bertoni, MD, MPH^¶, Donald M. Lloyd-Jones, MD, ScM^#, Eyal Shahar, MD, MPH^_**, Moyses Szklo, MD, DrPH and João A.C. Lima, MD^_*,,,_*

^_* Cardiology Division, Department of Medicine, Baltimore, Maryland
Department of Epidemiology, School of Public Health, Baltimore, Maryland
Department of Radiology, Johns Hopkins University, Baltimore, Maryland
Department of Biostatistics, University of Washington, Seattle, Washington
^|| Collaborative Health Studies Coordinating Center, University of Washington, Seattle, Washington
^¶ Department of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina
^# Department of Preventive Medicine, Northwestern University Medical School, Chicago, Illinois
^_** Division of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona.

View larger version (18K): [in this window] [in a new window] [Download PPT slide]   Figure 1 Cumulative Hazards of CHF by Categories of Inflammatory Markers, Metabolic Syndrome, and Albuminuria Nelson-Aalen plots of cumulative hazards for congestive heart failure (CHF) in the MESA (Multi-Ethnic Study of Atherosclerosis) study by categories of interleukin (IL)-6, C-reactive protein (CRP), metabolic syndrome, and albuminuria. The 75th percentiles for IL-6 and CRP were 1.9 and 4.3 mg/dl, respectively.