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A High Ankle-Brachial Index Is Associated With Increased Cardiovascular Disease Morbidity and Lower Quality of Life

Matthew A. Allison, MD, MPH^_*,_*, William R. Hiatt, MD, Alan T. Hirsch, MD^||,¶, Joseph R. Coll, PhD and Michael H. Criqui, MD, MPH^_*,

^_* Department of Family and Preventive Medicine, University of California San Diego, San Diego, California
Department of Medicine, University of California San Diego, San Diego, California
Department of Medicine, University of Colorado School of Medicine and the Colorado Prevention Center, Denver, Colorado
Department of Preventive Medicine and Biostatistics, University of Colorado School of Medicine and the Colorado Prevention Center, Denver, Colorado
^|| Vascular Medicine Program, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota
^¶ Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, Minnesota.

View larger version (37K): [in this window] [in a new window] [Download PPT slide]   Figure 1 Flow Diagram of Subjects Available for Analysis ABI = ankle-brachial index; PAD = peripheral arterial disease.

View larger version (17K): [in this window] [in a new window] [Download PPT slide]   Figure 2 Odds Ratios for CVD Comorbidities in Those With an ABI 1.40 Compared With an ABI Between 0.90 and 1.40 Compared with those with a normal ABI, individuals with a high ABI have significantly higher odds for congestive heart failure, stroke, foot ulcers, and neuropathy. Odds ratios are adjusted for age, gender, race, smoking, diabetes, hypertension, dyslipidemia, and body mass index. ABI = ankle-brachial index; CVD = cardiovascular disease.