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J Am Coll Cardiol, 2008; 51:1196-1202, doi:10.1016/j.jacc.2007.11.051
© 2008 by the American College of Cardiology Foundation
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Circulating Lipid Hydroperoxides Predict Cardiovascular Events in Patients With Stable Coronary Artery Disease

The PREVENT Study

Mary F. Walter, PhD*, Robert F. Jacob, PhD*,{ddagger}, Rebekah E. Bjork, BS*, Barrett Jeffers, PhD{dagger}, Jan Buch, MD{dagger}, Yoshiko Mizuno, MD, PhD*,{ddagger}, R. Preston Mason, PhD*,{ddagger},* on behalf of the PREVENT Investigators

* Elucida Research, Beverly, Massachusetts
{dagger} Pfizer Inc., New York, New York
{ddagger} Cardiovascular Division, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts.


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  		Figure 1 Quartile Analysis of Serum LOOH Levels and Risk for Cardiovascular Events

Analysis of baseline lipid hydroperoxide (LOOH) levels in patients with documented coronary artery disease for combined (A) and individual (B) events and procedures. CABG = coronary artery bypass graft; CHF = congestive heart failure; HR = hazard ratio; MI = myocardial infarction; PTCA = percutaneous transluminal coronary angioplasty.

 
 
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