N-Terminal B-Type Natriuretic Peptide Assessment Provides Incremental Prognostic Information in Patients With Acute Coronary Syndromes and Normal Troponin T Values Upon Admission
Michael Weber, MD*,*,
Oscar Bazzino, MD ,
Jose L. Navarro Estrada, MD,
Juan J. Fuselli, MD ,
Fernando Botto, MD ,
Diego Perez de Arenaza, MD,
Helge Möllmann, MD*,
Holger N. Nef, MD*,
Albrecht Elsässer, MD* and
Christian W. Hamm, MD*
* Kerckhoff Heart Center, Bad Nauheim, Germany
Hospital Italiano de Buenos Aires, Buenos Aires, Argentina
Centro de Educacion Medica e Investigative Clinicas, Buenos Aires, Argentina
Instituto Cardiovascular Buenos Aires, Buenos Aires, Argentina.
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Figure 1 Study Outline
Composition of the 2 different study cohorts and clinical outcome. ACS = acute coronary syndromes; PACS = Prognosis in Acute Coronary Syndromes; TnT = troponin T.
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Figure 2 NT-proBNP Values in Relation to Clinical Outcome
N-terminal pro–B-type natriuretic peptide (NT-proBNP) values of survivors and those who deceased during follow-up. Values are expressed as median and interquartile range. Other abbreviations as in Figure 1.
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Figure 3 Mortality Rate in Relation to NT-proBNP Values
Mortality rate in association with NT-proBNP values dichotomized at the calculated cutoff value of 474 pg/ml. Abbreviations as in Figures 1 and 2.
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Figure 4 Survival According to NT-proBNP Levels
Kaplan-Meier survival curves according to NT-proBNP values above (dashed lines) and below (solid lines) a cutoff value of 474 pg/ml. (A) Bad Nauheim ACS registry; (B) PACS registry. Abbreviations as in Figures 1 and 2.
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