Cockcroft-Gault Versus Modification of Diet in Renal DiseaseImportance of Glomerular Filtration Rate Formula for Classification of Chronic Kidney Disease in Patients With Non–ST-Segment Elevation Acute Coronary Syndromes
Chiara Melloni, MD, MHS*,
Eric D. Peterson, MD, MPH*,
Anita Y. Chen, MS*,
Lynda A. Szczech, MD, MSCE*,
L. Kristin Newby, MD, MHS*,
Robert A. Harrington, MD*,
W. Brian Gibler, MD ,
E. Magnus Ohman, MD*,
Sarah A. Spinler, PharmD, FCCP ,
Matthew T. Roe, MD, MHS* and
Karen P. Alexander, MD*,*
* Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina
Department of Emergency Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio
Philadelphia College of Pharmacy, University of the Sciences in Philadelphia, Philadelphia, Pennsylvania.
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Figure 1 Median Differences in eGFR (ml/min) Between MDRD and C-G Formulae Overall and by Subgroups
Data are truncated at –30 and 30. C-G = Cockcroft-Gault; eGFR = estimated glomerular filtration rate; MDRD = Modification of Diet in Renal Disease.
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Figure 2 Median Differences in eGFR (ml/min) Between MDRD and C-G Formulae by BMI Categories
Data are truncated at –30 and 30. BMI = body mass index; other abbreviations as in Figure 1.
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Figure 3 Scatterplot of the Agreement Between C-G and MDRD Formulae in the Estimation of GFR
Data in the figure represent 1% of a simple random sample of 46,942 patients. Lines drawn at 60 ml/min and 30 ml/min to emphasize categorical chronic kidney disease cut points as well as the linear relationship between formulae. Line of agreement shown. CrCl = creatinine clearance; other abbreviations as in Figure 1.
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