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J Am Coll Cardiol, 2007; 50:831-834, doi:10.1016/j.jacc.2007.05.018 (Published online 10 August 2007).
© 2007 by the American College of Cardiology Foundation
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Surgical Myectomy Versus Alcohol Septal Ablation for Obstructive Hypertrophic Cardiomyopathy

Will There Ever Be a Randomized Trial?

Iacopo Olivotto, MD*,*, Steve R. Ommen, MD{dagger}, Martin S. Maron, MD§, Franco Cecchi, MD* and Barry J. Maron, MD{ddagger}

* Referral Center for Myocardial Diseases, Department of Cardiology, Azienda Ospedaliera Universitaria Careggi, Florence, Italy
{dagger} Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota
{ddagger} Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota
§ Cardiology Division, Tufts–New England Medical Center, Boston, Massachusetts.


Figure 1
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Figure 1 Estimates for a Theoretical Surgical Myectomy Versus ASA Trial

Flow diagrams comparing patient selection and recruitment in the BARI study (coronary artery bypass graft surgery [CABG] vs. percutaneous transluminal coronary angioplasty [PTCA]): a representative example of a coronary artery disease-related randomized trial (23) (left) and a hypothetical myectomy versus alcohol septal ablation (ASA) trial (right). HCM = hypertrophic cardiomyopathy.

 




 
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