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J Am Coll Cardiol, 2007; 50:591-596, doi:10.1016/j.jacc.2007.03.062 (Published online 29 July 2007).
© 2007 by the American College of Cardiology Foundation
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Aldosterone Receptor Antagonism Induces Reverse Remodeling When Added to Angiotensin Receptor Blockade in Chronic Heart Failure

Anna K.Y. Chan, MB, MRCP*, John E. Sanderson, MD, FRCP, FACC*,*, Tian Wang, PhD*, Wynnie Lam, FRCR{dagger}, Gabriel Yip, MD*, Mei Wang, MD, PhD*, Yat-Yin Lam, MB, MRCP*, Yan Zhang, PhD*, Leata Yeung, RN, MPhil*, Eugene B. Wu, MD*, Wilson W.M. Chan, MD*, John T.H. Wong, MB, MRCP*, Nina So, FRCR{dagger} and Cheuk-Man Yu, MD, FRCP*

* Division of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR, China
{dagger} Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR, China.


Figure 1
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  		Figure 1 Flow Chart Depicting the Design of the Study

ACEI = angiotensin-converting enzyme inhibition; CMR = cardiac magnetic resonance imaging; EF = ejection fraction; ETT = exercise treadmill time; NYHA = New York Heart Association.

 

Figure 2
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  		Figure 2 Serial Changes of LVEF, LVEDVI, and LVESVI by CMR

CMR = cardiac magnetic resonance imaging; LVEDVI = left ventricular end-diastolic volume index; LVEF = left ventricular ejection fraction; LVESVI = left ventricular end-systolic volume index.

 




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Copyright © 2007 by the American College of Cardiology Foundation.