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ACC/AHA 2008 Performance Measures for Adults With ST-Elevation and Non–ST-Elevation Myocardial Infarction

ACC/AHA 2008 Guidelines for the Management of Adults With Congenital Heart Disease
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J Am Coll Cardiol, 2007; 50:551-557, doi:10.1016/j.jacc.2007.04.050 (Published online 23 July 2007).
© 2007 by the American College of Cardiology Foundation
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Chronic Monotherapy With Rosuvastatin Prevents Progressive Left Ventricular Dysfunction and Remodeling in Dogs With Heart Failure

Valerio Zacà, MD, Sharad Rastogi, MD, Makoto Imai, MD, Mengjun Wang, MD, Victor G. Sharov, PhD, Alice Jiang, MD, Sidney Goldstein, MD, FACC and Hani N. Sabbah, PhD, FACC*

Department of Medicine, Division of Cardiovascular Medicine, Henry Ford Heart and Vascular Institute, Henry Ford Health System, Detroit, Michigan.


Figure 1
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  		Figure 1 Ventriculographic Measures of LV Function and Size

Bar graphs depicting change ({Delta}) in left ventricular (LV) ejection fraction (EF), LV end-diastolic volume (EDV), and LV end-systolic volume (ESV) between pretreatment and post-treatment in control dogs, dogs randomized to low-dose (LD) rosuvastatin (RSV), or dogs randomized to high-dose (HD) RSV. *p < 0.05 versus control group; {dagger}p < 0.05 versus LD RSV.

 

Figure 2
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  		Figure 2 TNF-{alpha} and MMP-2

Tumor necrosis factor (TNF)-{alpha} and matrix metalloproteinase (MMP)-2 protein level in densitometric units after 3 months of therapy with RSV. *p < 0.05 versus control animals; {dagger}p < 0.05 versus normal (NL); {ddagger}p < 0.05 versus LD RSV. Abbreviations as in Figure 1.

 

Figure 3
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  		Figure 3 Magnitude of Circulating BMSCs

Absolute number of circulating Sca-1–positive bone marrow-derived stem cells (BMSCs). *p < 0.05 versus control animals; {dagger}p < 0.05 versus normal (NL). Abbreviations as in Figure 1.

 
 
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