Outcome and Growth Potential of Left Heart Structures After Neonatal Intervention for Aortic Valve Stenosis
Ra K. Han, MD, FRCPC*,
Rebecca C. Gurofsky, BSc*,
Kyong-Jin Lee, MD, FRCPC*,
Anne I. Dipchand, MD, FRCPC*,
William G. Williams, MD, FRCSC ,
Jeffrey F. Smallhorn, MD, FRCPC* and
Brian W. McCrindle, MD, MPH, FRCPC*,*
* Division of Cardiology, Department of Pediatrics, University of Toronto, The Hospital for Sick Children, Toronto, Ontario, Canada
Division of Cardiovascular Surgery, Department of Surgery, University of Toronto, The Hospital for Sick Children, Toronto, Ontario, Canada.

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Figure 1 Longitudinal Trends in Aortic Valve Insufficiency to Aortic Valve Annulus Jet Width Ratio
Individual trends from initial intervention until reintervention, death, or last follow-up.
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Figure 4 Kaplan-Meier Curve Depicting Freedom From Reintervention Over Time
The solid line represents the Kaplan-Meier estimates, and the dashed lines represent 95% confidence intervals.
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Figure 5 Kaplan-Meier Curve Depicting Freedom From Aortic Valve Replacement Over Time
The solid line represents the Kaplan Meier estimates, and the dashed lines represent 95% confidence intervals.
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Figure 6 Longitudinal Trends for Left Heart Structures After Initial Intervention to Reintervention, Death, or Last Follow-Up
The solid dark lines represent overall trends from regression modeling, the dotted lines represent 2 SDs from the predicted trends, and the light lines indicate measurements for individual patients over time. There was no significant interaction between left ventricular endocardial length z-score and time, and thus a time trend line is not provided. AP = anteroposterior.
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Figure 8 Predicted Trends in LV Dimensions Stratified by Initial Grade of Aortic Valve Insufficiency
Trends since initial intervention. LV = left ventricular; LVED = left ventricular end-diastolic.
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