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J Am Coll Cardiol, 2007; 50:2406-2414, doi:10.1016/j.jacc.2007.07.082 (Published online 11 December 2007).
© 2007 by the American College of Cardiology Foundation
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Outcome and Growth Potential of Left Heart Structures After Neonatal Intervention for Aortic Valve Stenosis

Ra K. Han, MD, FRCPC*, Rebecca C. Gurofsky, BSc*, Kyong-Jin Lee, MD, FRCPC*, Anne I. Dipchand, MD, FRCPC*, William G. Williams, MD, FRCSC{dagger}, Jeffrey F. Smallhorn, MD, FRCPC* and Brian W. McCrindle, MD, MPH, FRCPC*,*

* Division of Cardiology, Department of Pediatrics, University of Toronto, The Hospital for Sick Children, Toronto, Ontario, Canada
{dagger} Division of Cardiovascular Surgery, Department of Surgery, University of Toronto, The Hospital for Sick Children, Toronto, Ontario, Canada.


Figure 1
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Figure 1 Longitudinal Trends in Aortic Valve Insufficiency to Aortic Valve Annulus Jet Width Ratio

Individual trends from initial intervention until reintervention, death, or last follow-up.

 

Figure 2
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Figure 2 Kaplan-Meier Curve Depicting Survival Over Time

The solid line represents the Kaplan-Meier estimates, and the dashed lines represent 95% confidence intervals.

 

Figure 3
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Figure 3 Flowchart of Patient Outcomes

 

Figure 4
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Figure 4 Kaplan-Meier Curve Depicting Freedom From Reintervention Over Time

The solid line represents the Kaplan-Meier estimates, and the dashed lines represent 95% confidence intervals.

 

Figure 5
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Figure 5 Kaplan-Meier Curve Depicting Freedom From Aortic Valve Replacement Over Time

The solid line represents the Kaplan Meier estimates, and the dashed lines represent 95% confidence intervals.

 

Figure 6
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Figure 6 Longitudinal Trends for Left Heart Structures After Initial Intervention to Reintervention, Death, or Last Follow-Up

The solid dark lines represent overall trends from regression modeling, the dotted lines represent 2 SDs from the predicted trends, and the light lines indicate measurements for individual patients over time. There was no significant interaction between left ventricular endocardial length z-score and time, and thus a time trend line is not provided. AP = anteroposterior.

 

Figure 7
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Figure 7 Predicted Z-Scores of Left Heart Structures After Initial Intervention Stratified by Initial Z-Score in Quartiles

AP = anteroposterior.

 

Figure 8
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Figure 8 Predicted Trends in LV Dimensions Stratified by Initial Grade of Aortic Valve Insufficiency

Trends since initial intervention. LV = left ventricular; LVED = left ventricular end-diastolic.

 




 
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