Submit Manuscripts
Author Information
Subscribe/Renew
Email Alerts
Feedback
RSS Feed

About the Journal
Editorial Board & Staff

Interventions Homepage Imaging Homepage Interventions Homepage Imaging Homepage

ACC.org
Cardiosmart
Cardiosource
CVN
Imaging Library
JACC Imaging
JACC Interventions

ACC/AHA 2008 Performance Measures for Adults With ST-Elevation and Non–ST-Elevation Myocardial Infarction

ACC/AHA 2008 Guidelines for the Management of Adults With Congenital Heart Disease
cardiology careers collections past issues search home
     

J Am Coll Cardiol, 2007; 50:1315-1323, doi:10.1016/j.jacc.2007.03.070 (Published online 14 September 2007).
© 2007 by the American College of Cardiology Foundation
This Article
Right arrow Abstract Freely available
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Penicka, M.
Right arrow Articles by Widimsky, P.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Penicka, M.
Right arrow Articles by Widimsky, P.

Severe Left Ventricular Dyssynchrony Is Associated With Poor Prognosis in Patients With Moderate Systolic Heart Failure Undergoing Coronary Artery Bypass Grafting

Martin Penicka, MD, PhD*,1,*, Jozef Bartunek, MD, PhD§,1, Otto Lang, MD, PhD{dagger}, Karel Medilek, MD{ddagger}, Petr Tousek, MD*, Marc Vanderheyden, MD§, Bernard De Bruyne, MD, PhD§, Michaela Maruskova, MD* and Petr Widimsky, MD, PhD*

* Cardiocenter, Department of Cardiology, Third Faculty of Medicine, Charles University, and University Hospital Kralovske Vinohrady, Prague, Czech Republic
{dagger} Department of Nuclear Medicine, Third Faculty of Medicine, Charles University, and University Hospital Kralovske Vinohrady, Prague, Czech Republic
{ddagger} Department of Cardiosurgery, Medical Faculty, Hradec Kralove, Czech Republic
§ Cardiovascular Center, OLV Hospital, Aalst, Belgium.


Figure 1
View larger version (9K):
[in this window]
[in a new window]
[Download PPT slide]
  		Figure 1 Pre-CABG Dyssynchrony and Myocardial Viability in 30-Day Survivors and Nonsurvivors

Degree of the pre-CABG left ventricular dyssynchrony (left) and degree of viable myocardium (right) in patients who died versus survived during the first 30 days after CABG. CABG = coronary artery bypass grafting.

 

Figure 2
View larger version (16K):
[in this window]
[in a new window]
[Download PPT slide]
  		Figure 2 Pre-CABG Dyssynchrony, Myocardial Viability, and 30-Day Mortality

Agreement between the presence (+DYS) or absence (–DYS) of severe pre-CABG left ventricular dyssynchrony (≥119 ms) (top), the absence (–viable) or presence (+ viable) of viable myocardium (<5 viable segments) (bottom) and the 30-day mortality. AUC = area under curve; CABG = coronary artery bypass graft; DYS = dyssynchrony.

 

Figure 3
View larger version (16K):
[in this window]
[in a new window]
[Download PPT slide]
  		Figure 3 Accuracy of LV Dyssynchrony and Myocardial Viability to Predict Long-Term Clinical Events

Receiver-operating characteristic curves to predict clinical events occurring from day 31 after CABG to the end of the follow-up period for pre- and post-CABG left ventricular dyssynchrony and the number of dysfunctional but viable segments. Sp = specificity; Ss = sensitivity; other abbreviations as in Figure 2.

 

Figure 4
View larger version (24K):
[in this window]
[in a new window]
[Download PPT slide]
  		Figure 4 Long-Term Mortality and Hospitalizations According to Degree of Post-CABG DYS and Myocardial Viability

Kaplan-Meier estimates of the time to death from any cause or hospitalization for worsening heart failure between day 31 after CABG to the end of the follow-up period in patients without post-CABG dyssynchrony (<72 ms) and with large area (≥5 segments) of viable myocardium (blue solid line), patients without post-CABG dyssynchrony (<72 ms) and with small area (<5 segments) of viable myocardium (green dotted line), patients with significant post-CABG dyssynchrony (≥72 ms) and large area (≥5 segments) of viable myocardium (red solid line), and patients with significant post-CABG dyssynchrony (≥72 ms) and small area (<5 segments) of viable myocardium (orange dashed line). Pairwise comparison between groups is shown in accompanying table. CABG = coronary artery bypass grafting; DYS = dyssynchrony.

 
 
  cardiology careers collections past issues search home