Severe Left Ventricular Dyssynchrony Is Associated With Poor Prognosis in Patients With Moderate Systolic Heart Failure Undergoing Coronary Artery Bypass Grafting
Martin Penicka, MD, PhD*,1,*,
Jozef Bartunek, MD, PhD ,1,
Otto Lang, MD, PhD ,
Karel Medilek, MD ,
Petr Tousek, MD*,
Marc Vanderheyden, MD ,
Bernard De Bruyne, MD, PhD ,
Michaela Maruskova, MD* and
Petr Widimsky, MD, PhD*
* Cardiocenter, Department of Cardiology, Third Faculty of Medicine, Charles University, and University Hospital Kralovske Vinohrady, Prague, Czech Republic
Department of Nuclear Medicine, Third Faculty of Medicine, Charles University, and University Hospital Kralovske Vinohrady, Prague, Czech Republic
Department of Cardiosurgery, Medical Faculty, Hradec Kralove, Czech Republic
Cardiovascular Center, OLV Hospital, Aalst, Belgium.

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Figure 1 Pre-CABG Dyssynchrony and Myocardial Viability in 30-Day Survivors and Nonsurvivors
Degree of the pre-CABG left ventricular dyssynchrony (left) and degree of viable myocardium (right) in patients who died versus survived during the first 30 days after CABG. CABG = coronary artery bypass grafting.
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Figure 2 Pre-CABG Dyssynchrony, Myocardial Viability, and 30-Day Mortality
Agreement between the presence (+DYS) or absence (–DYS) of severe pre-CABG left ventricular dyssynchrony ( 119 ms) (top), the absence (–viable) or presence (+ viable) of viable myocardium (<5 viable segments) (bottom) and the 30-day mortality. AUC = area under curve; CABG = coronary artery bypass graft; DYS = dyssynchrony.
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Figure 3 Accuracy of LV Dyssynchrony and Myocardial Viability to Predict Long-Term Clinical Events
Receiver-operating characteristic curves to predict clinical events occurring from day 31 after CABG to the end of the follow-up period for pre- and post-CABG left ventricular dyssynchrony and the number of dysfunctional but viable segments. Sp = specificity; Ss = sensitivity; other abbreviations as in Figure 2.
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