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Long-Term Clinical Outcomes With Sirolimus-Eluting Coronary Stents

Five-Year Results of the RAVEL Trial

Marie-Claude Morice, MD, FACC, FESC^_*,_*, Patrick W. Serruys, MD, PhD, FACC, Paul Barragan, MD, Christoph Bode, MD, Gerrit-Anne Van Es, PhD^||, Hans-Peter Stoll, MD^¶, David Snead, PhD^#, Laura Mauri, MD, MSc, FACC^_**, Donald E. Cutlip, MD, FACC^_** and Eduardo Sousa, MD, PhD, FACC

^_* Institut Cardiovasculaire Paris Sud, Massy, France
Erasmus Medical Center, Rotterdam, the Netherlands
Clinique Beauregard, Marseille, France
Albert-Ludwigs-Universitätskliniken, Kardiologie, Freiburg, Germany
^|| Cardialysis, Rotterdam, the Netherlands
^¶ Cordis Clinical Research, Waterloo, Belgium
^# Cordis Clinical Research, Warren, New Jersey
^_** Harvard Clinical Research Institute, Boston, Massachusetts
Instituto Dante Pazzanese, Sao Paulo, Brazil.

View larger version (25K): [in this window] [in a new window] [Download PPT slide]   Figure 1 Flow of Patients Through the Trial LTF = lost to follow-up.

View larger version (12K): [in this window] [in a new window] [Download PPT slide]   Figure 2 Survival Free From Death or MI The sirolimus-eluting stent group is represented by a red line and the control group by a blue line. Error bars indicate ± 1.5 standard error. MI = myocardial infarction.

View larger version (13K): [in this window] [in a new window] [Download PPT slide]   Figure 3 Survival Free From MACE The sirolimus-eluting stent group is represented by a red line and the control group by a blue line. Error bars indicate ± 1.5 standard error. MACE = major adverse cardiac events.

View larger version (11K): [in this window] [in a new window] [Download PPT slide]   Figure 4 Survival Free From TLR The sirolimus-eluting stent group is represented by a red line and the control group by a blue line. Error bars indicate ± 1.5 standard error. TLR = target lesion revascularization.