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J Am Coll Cardiol, 2007; 50:1064-1069, doi:10.1016/j.jacc.2007.06.007 (Published online 23 August 2007).
© 2007 by the American College of Cardiology Foundation
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Post-Heart Transplant Diastolic Dysfunction Is a Risk Factor for Mortality

José A. Tallaj, MD*,{ddagger},*, James K. Kirklin, MD{dagger}, Robert N. Brown, BS{dagger}, Barry K. Rayburn, MD*, Robert C. Bourge, MD*, Raymond L. Benza, MD*, Laura Pinderski, MD, PhD*,§, Salpy Pamboukian, MD*, David C. McGiffin, MD{dagger} and David C. Naftel, PhD{dagger}

* Department of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, Alabama
{dagger} Department of Cardiovascular Surgery, University of Alabama at Birmingham, Birmingham, Alabama
{ddagger} Department of Medicine, Birmingham VA Medical Center, Birmingham, Alabama.


Figure 1
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Figure 1 RAP and Cardiac Mortality

Relationship between mean right atrial pressure (RAP) and the likelihood of subsequent cardiac mortality. The lines for each time point are essentially superimposable. The dashed lines represent the 20% confidence limits. cath = catheterization; Tx = transplant; UAB = University of Alabama at Birmingham.

 

Figure 2
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Figure 2 RAP/SV and Cardiac Mortality

Univariable depiction of the relationship between mean RAP divided by stroke volume (SV) and predicted cardiac mortality at 3 time points. Abbreviations as in Figure 1.

 

Figure 3
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Figure 3 RV DD and Cardiac Death

Actuarial survival for differing categories of right ventricular (RV) diastolic dysfunction (DD). The error bars enclose ± 1 SE. Right ventricular DD is defined in terms of RAP/SV, and at each time point (6 weeks, 6 months, 1 year) is the value of RAP/SV at which discrimination in survival is possible at p = 0.05. Abbreviations as in Figures 1 and 2.

 





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Copyright © 2007 by the American College of Cardiology Foundation.