Wireless Acoustic Communication With a Miniature Pressure Sensor in the Pulmonary Artery for Disease Surveillance and Therapy of Patients With Congestive Heart Failure
Yoseph Rozenman, MD, FACC*, ,1,*,
Robert S. Schwartz, MD, FACC ,2,
Hetal Shah, MPharm and
Keyur H. Parikh, MD, FACC
* The Heart Institute, E. Wolfson Medical Center (affiliated with the Sackler Faculty of Medicine Tel-Aviv University), Holon, Israel
Remon Medical Technologies, Caesarea, Israel
Minneapolis Heart Institute and Foundation, Minneapolis, Minnesota
The Heart Care Clinic, Ahmedabad, India.
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Figure 2 Angiographic Images During Device Implantation
(A) Human right pulmonary angiogram. (B) Angiography of the pig main pulmonary artery. Panels C and D are fluoroscopic images of the human and pig implants, respectively.
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Figure 3 Macroscopic View and Histologic Sections of the Implant After 6 Months
(A) Fluoroscopy of the implant in situ, after sacrifice. (B) Macroscopic view of the implant in the main pulmonary artery. Panels C and D are histologic sections at the level of the titanium case and the anchor, respectively.
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Figure 5 PA Pressure Measurements in Humans
Panels A and B are typical waveforms obtained simultaneously from the Millar catheter and the implant. Note the respiratory variation in panel B. Panels C and D are Bland-Altman and linear regression comparisons (respectively) of implant and Millar pulmonary artery (PA) diastolic pressures.
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Figure 6 Congestive Heart Failure Decompensation (Example)
(A and B) Regular follow-up while the patient was clinically stable; (C) during admission; (D) after diuretic therapy. PA = pulmonary artery; PAD = pulmonary artery diastolic pressure.
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