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J Am Coll Cardiol, 2007; 49:667-674, doi:10.1016/j.jacc.2006.09.048 (Published online 25 January 2007).
© 2007 by the American College of Cardiology Foundation
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Effects of Intravenous Atrial Natriuretic Peptide on Cardiac Sympathetic Nerve Activity and Left Ventricular Remodeling in Patients With First Anterior Acute Myocardial Infarction

Shu Kasama, MD*,*, Takuji Toyama, MD*, Takashi Hatori, MD*, Hiroyuki Sumino, MD*, Hisao Kumakura, MD{dagger}, Yoshiaki Takayama, MD{dagger}, Shuichi Ichikawa, MD{dagger}, Tadashi Suzuki, MD* and Masahiko Kurabayashi, MD*

* Department of Cardiovascular Medicine, Gunma University School of Medicine, Maebashi, Japan
{dagger} Department of Internal Medicine, Cardiovascular Hospital of Central Japan, Gunma, Japan.


Figure 1
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  		Figure 1 Comparison of Cardiac 123I-Meta-Iodobenzylguanidine Scintigraphic Findings 3 Weeks After Treatment

H/M = heart/mediastinum count; TDS = total defect score; WR = washout rate. *p < 0.05 compared with group A; {dagger}p < 0.005 compared with group A.

 

Figure 2
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  		Figure 2 Representative Single-Photon Emission Computerized Tomographic MIBG Images 3 Weeks After Treatment for Both Groups

ANP = atrial natriuretic peptide; HLA = horizontal long axis; ISDN = isosorbide dinitrate; MIBG = 123I-meta-Iodobenzylguanidine; SA = short axis; VLA = vertical long axis.

 

Figure 3
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  		Figure 3 Representative Anterior Planar Delayed MIBG Images 3 Weeks After Treatment for Both Groups

In these 2 examples, delayed heart/mediastinum (H/M) count ratio and washout rate were 2.01 and 36%, respectively, for a patient from group A and 1.55 and 52%, respectively, for a patient from group B. Abbreviations as in Figure 2.

 




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Copyright © 2007 by the American College of Cardiology Foundation.