Obstructive Sleep Apnea, Obesity, and the Risk of Incident Atrial Fibrillation
Apoor S. Gami, MD*, ,
Dave O. Hodge, MS ,
Regina M. Herges, BS,
Eric J. Olson, MD, ,
Jiri Nykodym, BS*,,
Tomas Kara, MD*, and
Virend K. Somers, MD, PhD, FACC*,,||,1,*
* Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, Minnesota
Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota
Department of Biostatistics, Mayo Clinic College of Medicine, Rochester, Minnesota
Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota
|| Division of Hypertension, Mayo Clinic College of Medicine, Rochester, Minnesota
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Figure 1 Incidence of AF Based on Presence or Absence of OSA
Cumulative frequency curves for incident atrial fibrillation (AF) for subjects <65 years of age with and without obstructive sleep apnea (OSA) during an average 4.7 years of follow-up. p = 0.002.
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Figure 2 Incidence of AF Based on the Severity of OSA and Obesity
Cumulative frequency of incident atrial fibrillation (AF) during an average 4.7 years of follow-up, based on interactions between the body mass index (BMI) and the apnea-hypopnea index (AHI). An AHI <5 represents no obstructive sleep apnea (OSA), an AHI 5 to 40 represents mild to moderate OSA, and an AHI >40 represents severe OSA. A BMI <25 represents normal weight, a BMI 25 to 30 kg/m2 represents overweight, and a BMI >30 kg/m2 represents obesity.
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