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J Am Coll Cardiol, 2007; 49:565-571, doi:10.1016/j.jacc.2006.08.060 (Published online 19 January 2007).
© 2007 by the American College of Cardiology Foundation
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Obstructive Sleep Apnea, Obesity, and the Risk of Incident Atrial Fibrillation

Apoor S. Gami, MD*,{dagger}, Dave O. Hodge, MS{ddagger}, Regina M. Herges, BS{ddagger}, Eric J. Olson, MD{dagger},§, Jiri Nykodym, BS*,{dagger}, Tomas Kara, MD*,{dagger} and Virend K. Somers, MD, PhD, FACC*,{dagger},||,1,*

* Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, Minnesota
{dagger} Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota
{ddagger} Department of Biostatistics, Mayo Clinic College of Medicine, Rochester, Minnesota
§ Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota
|| Division of Hypertension, Mayo Clinic College of Medicine, Rochester, Minnesota


Figure 1
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  		Figure 1 Incidence of AF Based on Presence or Absence of OSA

Cumulative frequency curves for incident atrial fibrillation (AF) for subjects <65 years of age with and without obstructive sleep apnea (OSA) during an average 4.7 years of follow-up. p = 0.002.

 

Figure 2
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  		Figure 2 Incidence of AF Based on the Severity of OSA and Obesity

Cumulative frequency of incident atrial fibrillation (AF) during an average 4.7 years of follow-up, based on interactions between the body mass index (BMI) and the apnea-hypopnea index (AHI). An AHI <5 represents no obstructive sleep apnea (OSA), an AHI 5 to 40 represents mild to moderate OSA, and an AHI >40 represents severe OSA. A BMI <25 represents normal weight, a BMI 25 to 30 kg/m2 represents overweight, and a BMI >30 kg/m2 represents obesity.

 




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Copyright © 2007 by the American College of Cardiology Foundation.