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J Am Coll Cardiol, 2007; 49:554-561, doi:10.1016/j.jacc.2006.07.072 (Published online 19 January 2007).
© 2007 by the American College of Cardiology Foundation
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Rosuvastatin Affecting Aortic Valve Endothelium to Slow the Progression of Aortic Stenosis

Luis M. Moura, MD*,{dagger}, Sandra F. Ramos, MSc{ddagger}, José L. Zamorano, MD, PhD{dagger}, Isabel M. Barros, MD*, Luis F. Azevedo, MD{ddagger}, Francisco Rocha-Gonçalves, MD, PhD{ddagger} and Nalini M. Rajamannan, MD§,1,*

* Hospital Pedro Hispano, Matosinhos, Portugal
{dagger} Hospital Clinico Universitário S. Carlos, Madrid, Spain
{ddagger} Oporto University Medical School, Oporto, Portugal
§ Northwestern University Feinberg School of Medicine, Chicago, Illinois


Figure 1
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Figure 1 Patient Flow Diagram

Flow chart of patient enrollment. pts = patients.

 

Figure 2
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Figure 2 Progression of Aortic Valve Stenosis in Patients Treated With Rosuvastatin Therapy and Untreated Patients

(A) Aortic jet velocity in treated versus untreated patients. (B) Aortic mean gradient in treated versus untreated patients. (C) Aortic valve area in treated versus untreated patients.

 

Figure 3
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Figure 3 Correlation of LDL Cholesterol With Echocardiographic Hemodynamic Measurements in Treated Patients

(A) Aortic jet velocity in treated patients. (B) Aortic mean gradient in treated patients. (C) Aortic valve area in treated patients. LDL = low-density lipoprotein.

 




 
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