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Multiple Less Common Genetic Variants Explain the Association of the Cholesteryl Ester Transfer Protein Gene With Coronary Artery Disease

Benjamin D. Horne, PhD, MPH^_*,,_*, Nicola J. Camp, PhD^,, Jeffrey L. Anderson, MD, FACC^_*,, Chrissa P. Mower^_*, Jessica L. Clarke, BS^_*, Matthew J. Kolek, BS^_*, John F. Carlquist, PhD^_*, for the Intermountain Heart Collaborative Study Group

^_* Cardiovascular Department, LDS Hospital, Intermountain Medical Center, University of Utah, Salt Lake City, Utah
Genetic Epidemiology Division, Department of Biomedical Informatics, University of Utah, Salt Lake City, Utah
Cardiology Division, Department of Internal Medicine, University of Utah, Salt Lake City, Utah
Genetic Research, Intermountain Healthcare, Salt Lake City, Utah.

View larger version (82K): [in this window] [in a new window] [Download PPT slide]   Figure 1 LD Structure of the 11 CETP tSNPs (Heat Map) Level of linkage disequilibrium (LD) (r2 value) is displayed within the shaded diamonds. CETP = cholesteryl ester transfer protein; tSNP = tagging single nucleotide polymorphism.