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J Am Coll Cardiol, 2007; 49:1943-1950, doi:10.1016/j.jacc.2007.02.037 (Published online 30 April 2007).
© 2007 by the American College of Cardiology Foundation
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Admission B-Type Natriuretic Peptide Levels and In-Hospital Mortality in Acute Decompensated Heart Failure

Gregg C. Fonarow, MD, FACC*,*, William F. Peacock, MD{dagger}, Christopher O. Phillips, MD, MPH{ddagger}, Michael M. Givertz, MD, FACC§, Margarita Lopatin, MS|| for the ADHERE Scientific Advisory Committee and Investigators

* Ahmanson–UCLA Cardiomyopathy Center, University of California, Los Angeles Medical Center, Los Angeles, California
{dagger} Department of Emergency Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio
{ddagger} Department of Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio
§ Department of Medicine, Brigham & Women’s Hospital, Boston, Massachusetts
|| Department of Biostatistics, Scios Inc., Mountain View, California.


Figure 1
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  		Figure 1 Distribution of BNP Values

Histogram of B-type natriuretic peptide (BNP) values (pg/ml) among the 48,629 hospitalization episodes.

 

Figure 2
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  		Figure 2 Relationship Between BNP Quartiles and In-Hospital Mortality

In-hospital mortality rates by B-type natriuretic peptide (BNP) quartiles (Q) (unadjusted) in the entire patient cohort (A), in patients with left ventricular ejection fraction (LVEF) <40% (n = 19,544) (B), in patients with LVEF ≥40% (n = 18,164) (C), and in patients with LVEF ≥50% (n = 12,631) (D). Each among-group comparison p < 0.0001.

 

Figure 3
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  		Figure 3 Scatterplot Smoother of BNP Levels and In-Hospital Mortality

Local regression scatterplot smoother (loess) of B-type natriuretic peptide (BNP) levels and in-hospital mortality risk. The vertical marks on the loess line indicate density of the data.

 




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Copyright © 2007 by the American College of Cardiology Foundation.