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J Am Coll Cardiol, 2007; 49:1874-1879, doi:10.1016/j.jacc.2006.10.078 (Published online 20 April 2007).
© 2007 by the American College of Cardiology Foundation
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Myocardial Delayed Enhancement by Magnetic Resonance Imaging in Patients With Muscular Dystrophy

Marly Conceição Silva, MD*, Zilda Maria Alves Meira, MD, PhD{dagger}, Juliana Gurgel Giannetti, MD, PhD{dagger}, Marcelo Moreira da Silva{dagger}, Alysson Félix Oliveira Campos, RT*, Márcia de Melo Barbosa, MD, PhD*, Geraldo Moll Starling Filho, MD*, Rogério de Aguiar Ferreira, MD*, Mayana Zatz, PhD{ddagger} and Carlos Eduardo Rochitte, MD, PhD*,§,*

* Axial Centro de Imagem, Belo Horizonte, Minas Gerais, Brazil
{dagger} Federal University of Minas Gerais Medical School, Minas Gerais, Brazil
{ddagger} Human Genome Research Center, Biosciences Institute, University of São Paulo, São Paulo, Brazil
§ Heart Institute (InCor) University of São Paulo Medical School, São Paulo, Brazil.


Figure 1
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  		Figure 1 Myocardial Fibrosis in Duchenne and Becker Muscular Dystrophy by CMR

Adjacent short-axis (SA) and long-axis (LA) views of 2 patients with muscular dystrophy (top: Duchenne, bottom: Becker) by cardiovascular magnetic resonance (CMR) using myocardial delayed enhancement technique. Between arrows are regions of myocardial delayed enhancement indicating myocardial fibrosis.

 

Figure 2
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  		Figure 2 Myocardial Fibrosis and Dysfunction in Muscular Dystrophy by Cardiovascular Magnetic Resonance

A patient example with Duchenne muscular dystrophy showing lateral myocardial delayed enhancement (MDE) and lateral akinesia (compare the wall thickening between septal [black arrowheads] and lateral [white arrowheads] walls) and global left ventricular dysfunction (left ventricular ejection fraction 41%).

 

Figure 3
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  		Figure 3 Absence of Myocardial Fibrosis and Normal Function in Muscular Dystrophy by Cardiovascular Magnetic Resonance

A patient with Duchenne muscular dystrophy showing no myocardial delayed enhancement (MDE) and normal global and segmental left ventricular function.

 




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