J Am Coll Cardiol, 2007; 49:1763-1769, doi:10.1016/j.jacc.2006.11.052 (Published online 13 April 2007). © 2007 by the American College of Cardiology Foundation

This Article Abstract Full Text Full Text (PDF) View Study Group and Centers Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in Web of Science Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Web of Science (45) Citing Articles via Google Scholar Google Scholar Articles by Poldermans, D. Search for Related Content PubMed Articles by Poldermans, D. Related Collections Related Article

A Clinical Randomized Trial to Evaluate the Safety of a Noninvasive Approach in High-Risk Patients Undergoing Major Vascular Surgery

The DECREASE-V Pilot Study

Don Poldermans, MD^_*,_*, Olaf Schouten, MD, Radosav Vidakovic, MD, Jeroen J. Bax, MD, Ian R. Thomson, MD^||, Sanne E. Hoeks, MSc, Harm H.H. Feringa, MD, Martin Dunkelgrün, MD, Peter de Jaegere, MD, Alexander Maat, MD^¶, Marc R.H.M. van Sambeek, MD, Miklos D. Kertai, MD^_*, Eric Boersma, PhD for the DECREASE Study Group

^_* Department of Anesthesiology, Erasmus Medical Center, Rotterdam, the Netherlands
Department of Vascular Surgery, Erasmus Medical Center, Rotterdam, the Netherlands
Department of Cardiology, Erasmus Medical Center, Rotterdam, the Netherlands
^¶ Department of Cardiothoracic Surgery, Erasmus Medical Center, Rotterdam, the Netherlands
Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands
^|| Department of Anesthesiology, University of Alberta, Winnipeg, Manitoba, Canada.

View larger version (12K): [in this window] [in a new window] [Download PPT slide]   Figure 1 Flowchart of the Study Cardiac risk factors included age over 70 years, angina pectoris, prior myocardial infarction (MI) on the basis of history or a finding of pathologic Q waves on electrocardiography, compensated congestive heart failure or a history of congestive heart failure, current treatment for diabetes mellitus, renal dysfunction (serum creatinine >160 µmol/l), and prior stroke or transient ischemic attack. Patients with >3 risk factors and extensive ischemia were randomly (1:1) assigned to coronary revascularization.

View larger version (5K): [in this window] [in a new window] [Download PPT slide]   Figure 2 Incidence of All-Cause Death or Myocardial Infarction During 1-Year Follow-Up According to the Allocated Strategy in Patients With 3 or More Cardiac Risk Factors With Extensive Stress-Induced Ischemia Light line = best medical treatment only; dark line = best medical treatment and prophylactic revascularization.