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J Am Coll Cardiol, 2007; 49:1753-1762, doi:10.1016/j.jacc.2007.01.067 (Published online 13 April 2007).
© 2007 by the American College of Cardiology Foundation
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Safety of Aggressive Lipid Management

Michael H. Davidson, MD, FACC*,* and Jennifer G. Robinson, MD, MPH{dagger}

* Radiant Research, Rush University Medical Center, Chicago, Illinois
{dagger} University of Iowa, Iowa City, Iowa.


Figure 1
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  		Figure 1 Incidence of Muscle Symptoms With CK Elevations >10x ULN and Rhabdomyolysis

Included only cardiovascular event trials for which these data were reported (2–4,7,25–27). CK = creatine kinase; LDL = low-density lipoprotein; OR = odds ratio; ULN = upper limit of normal.

 

Figure 2
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  		Figure 2 Incidence of ALT Elevations >3x ULN on 2 or More Consecutive Occasions

Included only cardiovascular event trials for which these data were reported (2–4,7). Abbreviations as in Figure 1.

 




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Copyright © 2007 by the American College of Cardiology Foundation.