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J Am Coll Cardiol, 2007; 49:1708-1714, doi:10.1016/j.jacc.2007.01.063 (Published online 4 April 2007).
© 2007 by the American College of Cardiology Foundation
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Phase Analysis of Gated Myocardial Perfusion Single-Photon Emission Computed Tomography Compared With Tissue Doppler Imaging for the Assessment of Left Ventricular Dyssynchrony

Maureen M. Henneman, MD*, Ji Chen, PhD||, Claudia Ypenburg, MD*, Petra Dibbets, MSc{dagger}, Gabe B. Bleeker, MD*,{ddagger}, Eric Boersma, PhD§, Marcel P. Stokkel, MD, PhD{dagger}, Ernst E. van der Wall, MD, PhD*,{ddagger}, Ernest V. Garcia, PhD|| and Jeroen J. Bax, MD, PhD*,*

* Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands
{dagger} Department of Nuclear Medicine, Leiden University Medical Center, Leiden, the Netherlands
{ddagger} The Interuniversity Cardiology Institute of the Netherlands, Utrecht, the Netherlands
§ Department of Epidemiology and Statistics, Erasmus University, Rotterdam, the Netherlands
|| Department of Radiology, Emory University School of Medicine, Atlanta, Georgia.


Figure 1
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  		Figure 1 Phase Analysis With GMPS

(A) Example of a patient without left ventricular (LV) dyssynchrony on gated myocardial perfusion single-photon emission computed tomography (GMPS). The non-normalized (upper panel) and normalized (lower panel) phase distributions are nearly uniform, and the corresponding phase histograms are highly peaked, narrow distributions. (B) Example of a patient with LV dyssynchrony derived from GMPS. The non-normalized (upper panel) and normalized (lower panel) phase distributions show significant non-uniformity and the corresponding phase histograms are widely spread distributions.

 

Figure 2
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  		Figure 2 Histogram Bandwidth Derived From GMPS Versus LV Dyssynchrony Assessed With TDI

Linear regression plot shows correlation between histogram bandwidth assessed from gated myocardial perfusion single-photon emission computed tomography (GMPS) and left ventricular (LV) dyssynchrony assessed with tissue Doppler imaging (TDI).

 

Figure 3
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  		Figure 3 Phase SD Derived From GMPS Versus LV Dyssynchrony Assessed With TDI

Linear regression plot shows correlation between phase standard deviation (SD) assessed from gated myocardial perfusion single-photon emission computed tomography (GMPS) and left ventricular (LV) dyssynchrony assessed with tissue Doppler imaging (TDI).

 

Figure 4
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  		Figure 4 Histogram Skewness Derived From GMPS Versus LV Dyssynchrony Assessed With TDI

Linear regression plot shows correlation between histogram skewness assessed from gated myocardial perfusion single-photon emission computed tomography (GMPS) and left ventricular (LV) dyssynchrony assessed with tissue Doppler imaging (TDI).

 

Figure 5
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  		Figure 5 Histogram Kurtosis Derived From GMPS Versus LV Dyssynchrony Assessed With TDI

Linear regression plot shows correlation between histogram kurtosis assessed from gated myocardial perfusion single-photon emission computed tomography (GMPS) and left ventricular (LV) dyssynchrony assessed with tissue Doppler imaging (TDI).

 




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Copyright © 2007 by the American College of Cardiology Foundation.